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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C7 All Species: 4.55
Human Site: S237 Identified Species: 11.11
UniProt: P10643 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10643 NP_000578.2 843 93518 S237 S S S R S Y T S H T N E I H K
Chimpanzee Pan troglodytes P61134 934 104929 E291 F Y S S K R S E N I N H N S A
Rhesus Macaque Macaca mulatta XP_001085533 552 61618
Dog Lupus familis XP_546339 863 94923 S237 S S S Y N R I S H T S K T H E
Cat Felis silvestris
Mouse Mus musculus Q8K182 587 66062 S42 Q A V S C Q L S D W Y K W T D
Rat Rattus norvegicus Q811M5 934 105095 E291 F Y S S K K S E N F Q R N S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518283 646 70390 S101 Q I M V V Q N S V E V A Q F I
Chicken Gallus gallus XP_424774 443 50189
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665979 820 92351 V238 L L I I R N E V E V A Q F Q N
Tiger Blowfish Takifugu rubipres P79755 586 65179 R41 A V N C V W S R W A P W S S C
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.3 60.8 79.2 N.A. 21.9 29.9 N.A. 30.3 33.3 N.A. 45.2 20.6 N.A. N.A. N.A. N.A.
Protein Similarity: 100 49.2 62.9 87.9 N.A. 36.6 47.9 N.A. 44.1 42.7 N.A. 61.7 36.3 N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 0 46.6 N.A. 6.6 6.6 N.A. 6.6 0 N.A. 0 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 0 73.3 N.A. 20 20 N.A. 6.6 0 N.A. 6.6 26.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 0 0 0 10 10 10 0 0 10 % A
% Cys: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 10 20 10 10 0 10 0 0 10 % E
% Phe: 20 0 0 0 0 0 0 0 0 10 0 0 10 10 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 20 0 0 10 0 20 0 % H
% Ile: 0 10 10 10 0 0 10 0 0 10 0 0 10 0 10 % I
% Lys: 0 0 0 0 20 10 0 0 0 0 0 20 0 0 10 % K
% Leu: 10 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 10 10 10 0 20 0 20 0 20 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 20 0 0 0 0 20 0 0 0 0 10 10 10 10 0 % Q
% Arg: 0 0 0 10 10 20 0 10 0 0 0 10 0 0 0 % R
% Ser: 20 20 40 30 10 0 30 40 0 0 10 0 10 30 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 20 0 0 10 10 0 % T
% Val: 0 10 10 10 20 0 0 10 10 10 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 10 10 0 10 10 0 0 % W
% Tyr: 0 20 0 10 0 10 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _