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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR1A
All Species:
36.67
Human Site:
Y231
Identified Species:
57.62
UniProt:
P10644
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10644
NP_002725.1
381
42982
Y231
W
G
I
D
R
D
S
Y
R
R
I
L
M
G
S
Chimpanzee
Pan troglodytes
XP_511647
260
29299
S139
I
E
K
N
V
L
F
S
H
L
D
D
N
E
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537577
381
43019
Y231
W
G
I
D
R
D
S
Y
R
R
I
L
M
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBC7
381
43167
Y231
W
G
I
D
R
D
S
Y
R
R
I
L
M
G
S
Rat
Rattus norvegicus
P09456
381
43076
Y231
W
G
I
D
R
D
S
Y
R
R
I
L
M
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509586
626
69567
Y476
W
G
I
D
R
D
S
Y
R
R
I
L
M
G
S
Chicken
Gallus gallus
Q5ZM91
382
43332
Y232
W
G
I
D
R
D
S
Y
R
R
I
L
M
G
S
Frog
Xenopus laevis
NP_001085084
381
43157
Y231
W
G
I
D
R
D
S
Y
R
R
I
L
M
G
S
Zebra Danio
Brachydanio rerio
NP_001017732
379
43009
Y229
W
G
I
D
R
D
S
Y
R
R
I
L
M
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16905
376
42221
Y226
W
G
I
D
R
D
S
Y
R
R
I
L
M
G
S
Honey Bee
Apis mellifera
XP_396167
372
41646
E239
R
K
R
K
M
Y
E
E
F
L
S
R
V
S
I
Nematode Worm
Caenorhab. elegans
P30625
366
41449
R228
M
G
S
V
T
K
K
R
K
M
Y
D
E
F
L
Sea Urchin
Strong. purpuratus
Q26619
369
41770
K236
I
Y
E
E
L
L
E
K
V
S
I
F
K
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
F278
W
A
L
D
R
L
T
F
R
K
I
L
L
G
S
Red Bread Mold
Neurospora crassa
Q01386
385
42138
F237
W
A
L
D
R
V
T
F
R
R
I
L
M
E
S
Conservation
Percent
Protein Identity:
100
68.2
N.A.
97.9
N.A.
96.8
97.3
N.A.
58.7
92.4
92.6
91.5
N.A.
71.3
74
57.7
39.3
Protein Similarity:
100
68.2
N.A.
98.1
N.A.
97.3
98.4
N.A.
60
96
95.8
95.8
N.A.
81.6
85.3
73.4
56.9
P-Site Identity:
100
0
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
0
6.6
6.6
P-Site Similarity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
6.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
34
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.7
52.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
74
0
60
0
0
0
0
7
14
0
0
0
% D
% Glu:
0
7
7
7
0
0
14
7
0
0
0
0
7
14
0
% E
% Phe:
0
0
0
0
0
0
7
14
7
0
0
7
0
7
0
% F
% Gly:
0
67
0
0
0
0
0
0
0
0
0
0
0
67
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
14
0
60
0
0
0
0
0
0
0
80
0
0
0
7
% I
% Lys:
0
7
7
7
0
7
7
7
7
7
0
0
7
0
0
% K
% Leu:
0
0
14
0
7
20
0
0
0
14
0
74
7
0
14
% L
% Met:
7
0
0
0
7
0
0
0
0
7
0
0
67
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
7
0
74
0
0
7
74
67
0
7
0
0
7
% R
% Ser:
0
0
7
0
0
0
60
7
0
7
7
0
0
14
74
% S
% Thr:
0
0
0
0
7
0
14
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
7
7
7
0
0
7
0
0
0
7
0
0
% V
% Trp:
74
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
7
0
60
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _