KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHGA
All Species:
11.21
Human Site:
T251
Identified Species:
30.83
UniProt:
P10645
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10645
NP_001266.1
457
50688
T251
V
P
E
E
E
G
P
T
V
V
L
N
P
H
P
Chimpanzee
Pan troglodytes
XP_510135
662
72241
T454
V
P
E
E
E
G
P
T
V
V
L
N
P
H
P
Rhesus Macaque
Macaca mulatta
XP_001092629
458
50713
T250
V
P
E
E
E
S
P
T
A
A
L
K
P
H
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P26339
463
51771
T259
A
G
P
E
E
V
P
T
A
A
S
S
S
H
F
Rat
Rattus norvegicus
P10354
466
52006
A265
G
P
K
E
V
P
T
A
A
S
S
S
H
F
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510676
470
52538
K240
E
E
E
E
E
G
E
K
G
I
N
P
Q
N
D
Chicken
Gallus gallus
XP_421330
466
53236
P259
E
D
D
G
E
D
A
P
G
E
E
D
P
T
E
Frog
Xenopus laevis
NP_001088193
438
49611
T245
K
R
D
F
E
K
E
T
P
K
E
D
T
N
E
Zebra Danio
Brachydanio rerio
NP_001006059
362
41132
D191
Q
E
E
A
T
I
R
D
E
E
R
K
H
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69
93.6
N.A.
N.A.
58.3
65.6
N.A.
48.5
44.6
38.7
33.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
69
95.1
N.A.
N.A.
68
74.8
N.A.
63.8
62.2
55.7
50.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
73.3
N.A.
N.A.
33.3
13.3
N.A.
26.6
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
N.A.
N.A.
40
26.6
N.A.
40
26.6
33.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
12
0
0
12
12
34
23
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
23
0
0
12
0
12
0
0
0
23
0
0
12
% D
% Glu:
23
23
56
67
78
0
23
0
12
23
23
0
0
0
23
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
12
12
% F
% Gly:
12
12
0
12
0
34
0
0
23
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
23
45
0
% H
% Ile:
0
0
0
0
0
12
0
0
0
12
0
0
0
0
0
% I
% Lys:
12
0
12
0
0
12
0
12
0
12
0
23
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
12
23
0
23
0
% N
% Pro:
0
45
12
0
0
12
45
12
12
0
0
12
45
0
34
% P
% Gln:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
12
0
0
0
0
12
0
0
0
12
0
0
0
0
% R
% Ser:
0
0
0
0
0
12
0
0
0
12
23
23
12
12
12
% S
% Thr:
0
0
0
0
12
0
12
56
0
0
0
0
12
12
0
% T
% Val:
34
0
0
0
12
12
0
0
23
23
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _