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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPPL2
All Species:
12.12
Human Site:
S196
Identified Species:
22.22
UniProt:
P10696
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10696
NP_112603.2
532
57377
S196
S
D
A
D
V
P
A
S
A
R
Q
E
G
C
Q
Chimpanzee
Pan troglodytes
XP_001146156
534
57545
S198
S
D
T
N
M
P
C
S
A
R
R
E
G
C
K
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
E323
S
D
N
E
M
P
P
E
A
L
S
Q
G
C
K
Dog
Lupus familis
XP_534605
554
59751
K199
S
D
A
N
M
P
A
K
A
L
E
D
G
C
Q
Cat
Felis silvestris
Mouse
Mus musculus
P24823
529
57193
S195
S
D
A
Q
M
P
A
S
A
L
Q
D
G
C
K
Rat
Rattus norvegicus
P15693
540
58384
S197
S
D
A
D
M
P
S
S
A
L
Q
E
G
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
D194
S
D
G
E
M
P
L
D
A
L
E
G
G
C
K
Frog
Xenopus laevis
NP_001091135
530
58155
N199
S
D
G
D
M
P
A
N
A
V
E
A
G
C
K
Zebra Danio
Brachydanio rerio
NP_001020359
521
56944
E200
S
D
K
E
L
T
S
E
A
V
A
G
G
C
Q
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
E199
S
D
S
V
M
P
A
E
A
V
Q
D
G
C
K
Fruit Fly
Dros. melanogaster
Q24238
596
65244
G229
E
V
P
A
E
S
V
G
F
H
V
D
I
A
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
E195
S
D
N
E
M
P
P
E
A
L
S
Q
G
C
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
V184
P
A
S
F
S
S
H
V
D
Y
R
W
Q
E
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
47.3
70.7
N.A.
73.8
72
N.A.
N.A.
56.2
59.9
56.2
54.3
40.2
N.A.
N.A.
N.A.
Protein Similarity:
100
94.3
59.2
79
N.A.
83.6
82.5
N.A.
N.A.
71
74.6
71.4
68.9
53.5
N.A.
N.A.
N.A.
P-Site Identity:
100
60
40
60
N.A.
66.6
73.3
N.A.
N.A.
40
53.3
40
53.3
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
66.6
86.6
N.A.
86.6
93.3
N.A.
N.A.
66.6
80
60
80
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
56.5
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
72.1
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
40
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
31
8
0
0
39
0
85
0
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
85
0
% C
% Asp:
0
85
0
24
0
0
0
8
8
0
0
31
0
0
8
% D
% Glu:
8
0
0
31
8
0
0
31
0
0
24
24
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
16
0
0
0
0
8
0
0
0
16
85
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
62
% K
% Leu:
0
0
0
0
8
0
8
0
0
47
0
0
0
0
0
% L
% Met:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
16
16
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
0
8
0
0
77
16
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
31
16
8
0
24
% Q
% Arg:
0
0
0
0
0
0
0
0
0
16
16
0
0
0
8
% R
% Ser:
85
0
16
0
8
16
16
31
0
0
16
0
0
0
0
% S
% Thr:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
8
8
0
8
8
0
24
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _