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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPPL2
All Species:
15.15
Human Site:
S276
Identified Species:
27.78
UniProt:
P10696
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10696
NP_112603.2
532
57377
S276
R
T
E
L
L
Q
A
S
L
D
P
S
V
T
H
Chimpanzee
Pan troglodytes
XP_001146156
534
57545
S278
R
A
E
R
M
H
A
S
L
D
P
S
V
T
H
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
L406
N
R
T
E
L
L
T
L
D
P
H
N
V
D
Y
Dog
Lupus familis
XP_534605
554
59751
S279
R
T
A
L
I
Q
A
S
Q
D
A
S
V
T
H
Cat
Felis silvestris
Mouse
Mus musculus
P24823
529
57193
S275
R
S
E
L
I
Q
A
S
L
N
R
S
V
T
H
Rat
Rattus norvegicus
P15693
540
58384
S277
R
E
Q
L
M
Q
A
S
Q
D
P
A
V
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
L277
H
R
R
E
L
L
A
L
N
V
S
R
V
D
F
Frog
Xenopus laevis
NP_001091135
530
58155
I278
N
K
E
Q
L
D
K
I
D
V
S
S
A
T
H
Zebra Danio
Brachydanio rerio
NP_001020359
521
56944
V276
N
K
Q
Q
F
D
A
V
N
E
D
K
T
D
Y
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
L281
N
K
K
Q
L
L
S
L
N
P
N
N
V
D
Y
Fruit Fly
Dros. melanogaster
Q24238
596
65244
V314
N
R
K
D
L
L
N
V
N
V
K
K
V
D
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
L278
N
R
T
E
L
L
A
L
D
P
S
R
V
D
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
H265
F
D
S
L
L
K
S
H
G
E
N
V
T
L
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
47.3
70.7
N.A.
73.8
72
N.A.
N.A.
56.2
59.9
56.2
54.3
40.2
N.A.
N.A.
N.A.
Protein Similarity:
100
94.3
59.2
79
N.A.
83.6
82.5
N.A.
N.A.
71
74.6
71.4
68.9
53.5
N.A.
N.A.
N.A.
P-Site Identity:
100
73.3
13.3
73.3
N.A.
73.3
60
N.A.
N.A.
20
33.3
6.6
13.3
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
26.6
80
N.A.
93.3
80
N.A.
N.A.
20
33.3
26.6
40
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
56.5
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
72.1
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
62
0
0
0
8
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
16
0
0
24
31
8
0
0
47
0
% D
% Glu:
0
8
31
24
0
0
0
0
0
16
0
0
0
0
0
% E
% Phe:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
8
0
8
0
0
8
0
0
0
47
% H
% Ile:
0
0
0
0
16
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
24
16
0
0
8
8
0
0
0
8
16
0
0
0
% K
% Leu:
0
0
0
39
62
39
0
31
24
0
0
0
0
8
0
% L
% Met:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
47
0
0
0
0
0
8
0
31
8
16
16
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
24
24
0
0
0
8
% P
% Gln:
0
0
16
24
0
31
0
0
16
0
0
0
0
0
0
% Q
% Arg:
39
31
8
8
0
0
0
0
0
0
8
16
0
0
8
% R
% Ser:
0
8
8
0
0
0
16
39
0
0
24
39
0
0
0
% S
% Thr:
0
16
16
0
0
0
8
0
0
0
0
0
16
47
0
% T
% Val:
0
0
0
0
0
0
0
16
0
24
0
8
77
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
31
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _