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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPPL2
All Species:
34.24
Human Site:
S306
Identified Species:
62.78
UniProt:
P10696
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10696
NP_112603.2
532
57377
S306
R
D
S
T
L
D
P
S
L
M
E
M
T
E
A
Chimpanzee
Pan troglodytes
XP_001146156
534
57545
S308
X
D
S
T
L
D
L
S
Q
M
E
M
T
E
A
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
S436
R
N
N
V
T
D
P
S
L
S
E
M
V
V
V
Dog
Lupus familis
XP_534605
554
59751
S309
R
D
G
I
Q
D
P
S
L
M
E
M
T
E
A
Cat
Felis silvestris
Mouse
Mus musculus
P24823
529
57193
S305
R
D
P
A
Q
D
P
S
L
A
E
M
T
E
V
Rat
Rattus norvegicus
P15693
540
58384
S307
R
N
A
S
A
D
P
S
L
A
E
M
T
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
S307
R
N
N
E
T
D
P
S
L
S
E
M
V
A
V
Frog
Xenopus laevis
NP_001091135
530
58155
S308
R
N
T
T
T
D
P
S
I
V
E
L
T
E
I
Zebra Danio
Brachydanio rerio
NP_001020359
521
56944
S306
R
D
P
K
M
D
P
S
L
T
E
M
V
E
K
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
S311
R
N
P
E
T
D
P
S
L
T
E
M
V
E
V
Fruit Fly
Dros. melanogaster
Q24238
596
65244
L344
R
E
A
G
E
P
S
L
Q
E
M
T
E
T
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
S308
R
N
N
L
T
D
P
S
L
S
E
M
V
E
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
S295
R
D
E
K
E
Y
P
S
L
K
E
Q
V
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
47.3
70.7
N.A.
73.8
72
N.A.
N.A.
56.2
59.9
56.2
54.3
40.2
N.A.
N.A.
N.A.
Protein Similarity:
100
94.3
59.2
79
N.A.
83.6
82.5
N.A.
N.A.
71
74.6
71.4
68.9
53.5
N.A.
N.A.
N.A.
P-Site Identity:
100
80
46.6
80
N.A.
66.6
60
N.A.
N.A.
46.6
53.3
60
53.3
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
60
80
N.A.
66.6
80
N.A.
N.A.
60
86.6
66.6
60
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
56.5
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
72.1
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
53.3
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
8
0
0
0
0
16
0
0
0
8
31
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
47
0
0
0
85
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
8
16
16
0
0
0
0
8
93
0
8
70
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
0
0
0
16
0
0
0
0
0
8
0
0
0
8
8
% K
% Leu:
0
0
0
8
16
0
8
8
77
0
0
8
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
24
8
77
0
0
0
% M
% Asn:
0
47
24
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
24
0
0
8
85
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
16
0
0
0
16
0
0
8
0
0
0
% Q
% Arg:
93
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
16
8
0
0
8
93
0
24
0
0
0
0
0
% S
% Thr:
0
0
8
24
39
0
0
0
0
16
0
8
47
8
0
% T
% Val:
0
0
0
8
0
0
0
0
0
8
0
0
47
8
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _