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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPPL2
All Species:
27.27
Human Site:
S365
Identified Species:
50
UniProt:
P10696
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10696
NP_112603.2
532
57377
S365
E
R
A
G
Q
L
T
S
E
E
D
T
L
S
L
Chimpanzee
Pan troglodytes
XP_001146156
534
57545
S367
E
R
A
G
Q
L
T
S
E
E
D
T
L
S
L
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
S495
G
Q
A
G
S
M
T
S
L
E
D
T
L
T
V
Dog
Lupus familis
XP_534605
554
59751
S368
D
K
A
G
Q
L
T
S
E
R
D
T
L
T
L
Cat
Felis silvestris
Mouse
Mus musculus
P24823
529
57193
S364
D
K
A
D
I
R
T
S
E
Q
D
T
M
I
L
Rat
Rattus norvegicus
P15693
540
58384
N366
E
K
A
S
Q
L
T
N
E
K
D
T
L
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
A361
L
D
R
A
V
G
L
A
G
R
L
T
S
P
R
Frog
Xenopus laevis
NP_001091135
530
58155
N367
D
K
A
D
Q
L
T
N
E
I
D
T
L
T
V
Zebra Danio
Brachydanio rerio
NP_001020359
521
56944
S365
E
R
A
G
Q
L
T
S
E
L
D
T
L
S
V
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
S370
S
R
A
G
L
M
T
S
I
H
D
T
L
T
I
Fruit Fly
Dros. melanogaster
Q24238
596
65244
D404
Q
A
A
V
N
N
T
D
P
D
E
T
L
I
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
S367
G
K
A
G
T
M
T
S
Q
K
D
T
L
T
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
E360
Q
Y
V
L
E
F
A
E
N
S
D
T
E
T
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
47.3
70.7
N.A.
73.8
72
N.A.
N.A.
56.2
59.9
56.2
54.3
40.2
N.A.
N.A.
N.A.
Protein Similarity:
100
94.3
59.2
79
N.A.
83.6
82.5
N.A.
N.A.
71
74.6
71.4
68.9
53.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
73.3
N.A.
46.6
66.6
N.A.
N.A.
6.6
53.3
86.6
53.3
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
93.3
N.A.
73.3
93.3
N.A.
N.A.
13.3
86.6
93.3
73.3
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
56.5
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
72.1
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
46.6
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
85
8
0
0
8
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
8
0
16
0
0
0
8
0
8
85
0
0
0
0
% D
% Glu:
31
0
0
0
8
0
0
8
54
24
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
54
0
8
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
8
8
0
0
0
16
8
% I
% Lys:
0
39
0
0
0
0
0
0
0
16
0
0
0
0
0
% K
% Leu:
8
0
0
8
8
47
8
0
8
8
8
0
77
0
47
% L
% Met:
0
0
0
0
0
24
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
8
0
16
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% P
% Gln:
16
8
0
0
47
0
0
0
8
8
0
0
0
0
0
% Q
% Arg:
0
31
8
0
0
8
0
0
0
16
0
0
0
0
8
% R
% Ser:
8
0
0
8
8
0
0
62
0
8
0
0
8
24
0
% S
% Thr:
0
0
0
0
8
0
85
0
0
0
0
100
0
54
0
% T
% Val:
0
0
8
8
8
0
0
0
0
0
0
0
0
0
39
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _