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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPPL2
All Species:
36.36
Human Site:
T182
Identified Species:
66.67
UniProt:
P10696
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10696
NP_112603.2
532
57377
T182
P
A
G
A
Y
A
H
T
V
N
R
N
W
Y
S
Chimpanzee
Pan troglodytes
XP_001146156
534
57545
T184
P
A
G
T
Y
A
H
T
V
N
R
N
W
Y
S
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
S309
P
S
A
A
Y
A
H
S
A
D
R
D
W
Y
S
Dog
Lupus familis
XP_534605
554
59751
V185
P
A
G
T
Y
A
H
V
V
N
R
N
W
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
P24823
529
57193
T181
P
A
G
T
Y
A
H
T
V
N
R
G
W
Y
S
Rat
Rattus norvegicus
P15693
540
58384
T183
P
A
G
T
Y
A
H
T
V
N
R
D
W
Y
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
S180
P
S
A
A
Y
A
H
S
A
N
R
D
W
Y
S
Frog
Xenopus laevis
NP_001091135
530
58155
T185
P
S
G
T
Y
A
N
T
P
D
R
N
W
Y
S
Zebra Danio
Brachydanio rerio
NP_001020359
521
56944
T186
P
A
A
S
Y
S
H
T
P
E
R
G
W
Y
S
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
S185
P
S
A
S
Y
A
H
S
V
D
R
D
W
L
S
Fruit Fly
Dros. melanogaster
Q24238
596
65244
R215
T
Y
A
H
I
Y
D
R
D
W
E
C
D
T
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
S181
P
S
A
A
Y
A
H
S
A
D
R
D
W
Y
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
T170
L
T
G
L
V
V
T
T
R
I
T
D
A
T
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
47.3
70.7
N.A.
73.8
72
N.A.
N.A.
56.2
59.9
56.2
54.3
40.2
N.A.
N.A.
N.A.
Protein Similarity:
100
94.3
59.2
79
N.A.
83.6
82.5
N.A.
N.A.
71
74.6
71.4
68.9
53.5
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
60
86.6
N.A.
86.6
86.6
N.A.
N.A.
66.6
66.6
60
53.3
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
86.6
86.6
N.A.
86.6
93.3
N.A.
N.A.
86.6
86.6
73.3
86.6
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
56.5
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
72.1
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
60
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
47
47
31
0
77
0
0
24
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
8
31
0
47
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
54
0
0
0
0
0
0
0
0
16
0
0
0
% G
% His:
0
0
0
8
0
0
77
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
47
0
31
0
0
0
% N
% Pro:
85
0
0
0
0
0
0
0
16
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
8
0
85
0
0
0
0
% R
% Ser:
0
39
0
16
0
8
0
31
0
0
0
0
0
0
85
% S
% Thr:
8
8
0
39
0
0
8
54
0
0
8
0
0
16
0
% T
% Val:
0
0
0
0
8
8
0
8
47
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
85
0
0
% W
% Tyr:
0
8
0
0
85
8
0
0
0
0
0
0
0
77
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _