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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALPPL2 All Species: 22.12
Human Site: T207 Identified Species: 40.56
UniProt: P10696 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10696 NP_112603.2 532 57377 T207 E G C Q D I A T Q L I S N M D
Chimpanzee Pan troglodytes XP_001146156 534 57545 T209 E G C K D I A T Q L I S N M D
Rhesus Macaque Macaca mulatta XP_001109717 652 71041 Y334 Q G C K D I A Y Q L V H N I R
Dog Lupus familis XP_534605 554 59751 Q210 D G C Q D I A Q Q L I S N M E
Cat Felis silvestris
Mouse Mus musculus P24823 529 57193 T206 D G C K D I S T Q L I S N M D
Rat Rattus norvegicus P15693 540 58384 T208 E G C K D I A T Q L I S N M D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q92058 519 56742 R205 G G C K D I A R Q L V D N I P
Frog Xenopus laevis NP_001091135 530 58155 H210 A G C K D I A H Q L I S N V D
Zebra Danio Brachydanio rerio NP_001020359 521 56944 V211 G G C Q D I A V Q L I T N T D
Tiger Blowfish Takifugu rubipres NP_001027823 527 57490 R210 D G C K D I A R Q L F E N I P
Fruit Fly Dros. melanogaster Q24238 596 65244 E240 D I A R Q L V E N A P G N R F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001130844 524 57641 Y206 Q G C K D I A Y Q L M H N I K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P11491 566 62986 T195 W Q E D L I A T H Q L G E Y P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.5 47.3 70.7 N.A. 73.8 72 N.A. N.A. 56.2 59.9 56.2 54.3 40.2 N.A. N.A. N.A.
Protein Similarity: 100 94.3 59.2 79 N.A. 83.6 82.5 N.A. N.A. 71 74.6 71.4 68.9 53.5 N.A. N.A. N.A.
P-Site Identity: 100 93.3 53.3 80 N.A. 80 93.3 N.A. N.A. 53.3 73.3 73.3 53.3 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 80 93.3 N.A. 100 100 N.A. N.A. 73.3 86.6 80 73.3 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 56.5 N.A. N.A. 25.6 N.A.
Protein Similarity: N.A. 72.1 N.A. N.A. 41.7 N.A.
P-Site Identity: N.A. 53.3 N.A. N.A. 20 N.A.
P-Site Similarity: N.A. 80 N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 0 85 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 85 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 31 0 0 8 85 0 0 0 0 0 0 8 0 0 47 % D
% Glu: 24 0 8 0 0 0 0 8 0 0 0 8 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % F
% Gly: 16 85 0 0 0 0 0 0 0 0 0 16 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 8 0 0 16 0 0 0 % H
% Ile: 0 8 0 0 0 93 0 0 0 0 54 0 0 31 0 % I
% Lys: 0 0 0 62 0 0 0 0 0 0 0 0 0 0 8 % K
% Leu: 0 0 0 0 8 8 0 0 0 85 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 39 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 0 93 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 24 % P
% Gln: 16 8 0 24 8 0 0 8 85 8 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 0 0 16 0 0 0 0 0 8 8 % R
% Ser: 0 0 0 0 0 0 8 0 0 0 0 47 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 39 0 0 0 8 0 8 0 % T
% Val: 0 0 0 0 0 0 8 8 0 0 16 0 0 8 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 16 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _