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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPPL2
All Species:
23.64
Human Site:
T231
Identified Species:
43.33
UniProt:
P10696
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10696
NP_112603.2
532
57377
T231
K
Y
M
F
P
M
G
T
P
D
P
E
Y
P
D
Chimpanzee
Pan troglodytes
XP_001146156
534
57545
T233
K
Y
M
F
R
M
G
T
P
D
P
E
Y
P
D
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
N358
R
K
Y
M
Y
P
K
N
K
T
D
V
E
Y
E
Dog
Lupus familis
XP_534605
554
59751
T234
K
Y
M
F
P
K
G
T
P
D
P
E
Y
P
T
Cat
Felis silvestris
Mouse
Mus musculus
P24823
529
57193
T230
K
F
M
F
P
K
G
T
P
D
Q
E
Y
P
T
Rat
Rattus norvegicus
P15693
540
58384
T232
K
F
M
F
P
K
G
T
P
D
P
E
Y
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
N229
R
K
Y
M
F
P
K
N
T
S
D
V
E
Y
P
Frog
Xenopus laevis
NP_001091135
530
58155
T234
K
Y
M
T
P
V
G
T
P
D
P
E
Y
P
A
Zebra Danio
Brachydanio rerio
NP_001020359
521
56944
T235
Q
Y
M
F
P
R
E
T
T
D
P
E
Y
S
T
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
N234
R
K
Y
M
F
P
K
N
Q
V
D
V
E
Y
P
Fruit Fly
Dros. melanogaster
Q24238
596
65244
S264
P
M
G
I
L
N
A
S
E
V
K
T
T
I
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
N230
R
K
Y
M
Y
P
K
N
R
T
D
V
E
Y
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
Y219
G
G
G
R
S
H
F
Y
P
Q
G
E
K
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
47.3
70.7
N.A.
73.8
72
N.A.
N.A.
56.2
59.9
56.2
54.3
40.2
N.A.
N.A.
N.A.
Protein Similarity:
100
94.3
59.2
79
N.A.
83.6
82.5
N.A.
N.A.
71
74.6
71.4
68.9
53.5
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
0
86.6
N.A.
73.3
80
N.A.
N.A.
0
80
60
0
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
13.3
86.6
N.A.
80
86.6
N.A.
N.A.
6.6
86.6
66.6
6.6
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
56.5
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
72.1
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
54
31
0
0
0
16
% D
% Glu:
0
0
0
0
0
0
8
0
8
0
0
62
31
0
16
% E
% Phe:
0
16
0
47
16
0
8
0
0
0
0
0
0
0
8
% F
% Gly:
8
8
16
0
0
0
47
0
0
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
47
31
0
0
0
24
31
0
8
0
8
0
8
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
8
54
31
0
16
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
31
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
47
31
0
0
54
0
47
0
0
47
16
% P
% Gln:
8
0
0
0
0
0
0
0
8
8
8
0
0
0
0
% Q
% Arg:
31
0
0
8
8
8
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
8
0
8
0
0
0
8
8
% S
% Thr:
0
0
0
8
0
0
0
54
16
16
0
8
8
0
24
% T
% Val:
0
0
0
0
0
8
0
0
0
16
0
31
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
39
31
0
16
0
0
8
0
0
0
0
54
31
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _