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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPPL2
All Species:
14.55
Human Site:
T429
Identified Species:
26.67
UniProt:
P10696
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10696
NP_112603.2
532
57377
T429
D
G
A
R
P
D
V
T
E
S
E
S
G
S
P
Chimpanzee
Pan troglodytes
XP_001146156
534
57545
T431
D
G
A
R
P
D
V
T
E
S
E
S
G
S
P
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
V559
V
G
G
E
R
E
N
V
S
M
V
D
Y
A
H
Dog
Lupus familis
XP_534605
554
59751
S432
G
V
P
R
P
N
F
S
D
A
E
S
R
D
P
Cat
Felis silvestris
Mouse
Mus musculus
P24823
529
57193
T428
N
G
A
R
A
D
V
T
E
E
E
S
S
N
P
Rat
Rattus norvegicus
P15693
540
58384
T430
S
G
N
R
P
N
V
T
D
A
E
S
G
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
G425
P
G
Y
K
I
V
G
G
E
R
E
N
V
S
A
Frog
Xenopus laevis
NP_001091135
530
58155
N431
D
Q
G
R
P
N
V
N
S
N
L
S
E
D
V
Zebra Danio
Brachydanio rerio
NP_001020359
521
56944
N429
N
G
T
R
P
D
V
N
E
S
V
S
G
R
D
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
V434
V
N
G
G
R
E
N
V
S
A
I
D
Y
Q
E
Fruit Fly
Dros. melanogaster
Q24238
596
65244
P468
H
L
A
N
D
S
R
P
Q
N
S
S
N
M
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
V431
V
D
G
E
R
E
N
V
S
M
V
D
Y
A
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
S424
V
H
E
H
K
G
A
S
S
K
I
E
N
F
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
47.3
70.7
N.A.
73.8
72
N.A.
N.A.
56.2
59.9
56.2
54.3
40.2
N.A.
N.A.
N.A.
Protein Similarity:
100
94.3
59.2
79
N.A.
83.6
82.5
N.A.
N.A.
71
74.6
71.4
68.9
53.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
33.3
N.A.
66.6
53.3
N.A.
N.A.
26.6
33.3
60
0
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
60
N.A.
80
73.3
N.A.
N.A.
40
46.6
66.6
13.3
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
56.5
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
72.1
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
31
0
8
0
8
0
0
24
0
0
0
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
8
0
0
8
31
0
0
16
0
0
24
0
24
8
% D
% Glu:
0
0
8
16
0
24
0
0
39
8
47
8
8
0
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% F
% Gly:
8
54
31
8
0
8
8
8
0
0
0
0
31
0
0
% G
% His:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
16
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
16
0
0
0
8
% I
% Lys:
0
0
0
8
8
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
16
0
0
0
8
0
% M
% Asn:
16
8
8
8
0
24
24
16
0
16
0
8
16
8
0
% N
% Pro:
8
0
8
0
47
0
0
8
0
0
0
0
0
0
31
% P
% Gln:
0
8
0
0
0
0
0
0
8
0
0
0
0
8
0
% Q
% Arg:
0
0
0
54
24
0
8
0
0
8
0
0
8
8
0
% R
% Ser:
8
0
0
0
0
8
0
16
39
24
8
62
8
24
0
% S
% Thr:
0
0
8
0
0
0
0
31
0
0
0
0
0
0
0
% T
% Val:
31
8
0
0
0
8
47
24
0
0
24
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
24
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _