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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPPL2
All Species:
6.06
Human Site:
T501
Identified Species:
11.11
UniProt:
P10696
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10696
NP_112603.2
532
57377
T501
D
L
A
P
R
A
G
T
T
D
A
A
H
P
G
Chimpanzee
Pan troglodytes
XP_001146156
534
57545
T503
D
L
A
P
P
A
G
T
T
D
A
A
H
P
G
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
L622
A
A
C
I
G
A
N
L
D
H
C
A
P
A
S
Dog
Lupus familis
XP_534605
554
59751
S504
R
F
P
T
P
S
L
S
A
R
R
A
L
A
G
Cat
Felis silvestris
Mouse
Mus musculus
P24823
529
57193
A498
D
C
G
L
A
S
P
A
G
Q
S
S
A
V
S
Rat
Rattus norvegicus
P15693
540
58384
E502
G
L
A
P
P
A
D
E
N
R
P
T
T
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
I489
A
M
A
Y
A
A
C
I
G
P
N
R
A
H
C
Frog
Xenopus laevis
NP_001091135
530
58155
P496
L
P
S
Y
K
D
C
P
S
Q
N
N
N
A
S
Zebra Danio
Brachydanio rerio
NP_001020359
521
56944
S491
A
A
C
I
E
P
Y
S
D
C
Q
L
H
D
S
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
R497
A
S
C
I
G
Q
N
R
Q
H
C
A
G
H
N
Fruit Fly
Dros. melanogaster
Q24238
596
65244
K554
D
D
S
C
E
D
H
K
D
G
Q
K
D
R
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
L494
A
S
C
I
G
A
N
L
D
H
C
A
W
A
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
I491
H
S
A
V
D
V
N
I
Y
A
Y
A
N
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
47.3
70.7
N.A.
73.8
72
N.A.
N.A.
56.2
59.9
56.2
54.3
40.2
N.A.
N.A.
N.A.
Protein Similarity:
100
94.3
59.2
79
N.A.
83.6
82.5
N.A.
N.A.
71
74.6
71.4
68.9
53.5
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
13.3
13.3
N.A.
6.6
33.3
N.A.
N.A.
13.3
0
6.6
6.6
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
13.3
26.6
N.A.
26.6
33.3
N.A.
N.A.
20
26.6
13.3
6.6
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
56.5
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
72.1
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
16
39
0
16
47
0
8
8
8
16
54
16
31
0
% A
% Cys:
0
8
31
8
0
0
16
0
0
8
24
0
0
0
8
% C
% Asp:
31
8
0
0
8
16
8
0
31
16
0
0
8
8
0
% D
% Glu:
0
0
0
0
16
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
24
0
16
0
16
8
0
0
8
0
24
% G
% His:
8
0
0
0
0
0
8
0
0
24
0
0
24
16
0
% H
% Ile:
0
0
0
31
0
0
0
16
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
8
0
0
0
8
0
8
8
% K
% Leu:
8
24
0
8
0
0
8
16
0
0
0
8
8
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
31
0
8
0
16
8
16
0
8
% N
% Pro:
0
8
8
24
24
8
8
8
0
8
8
0
8
24
8
% P
% Gln:
0
0
0
0
0
8
0
0
8
16
16
0
0
0
0
% Q
% Arg:
8
0
0
0
8
0
0
8
0
16
8
8
0
8
0
% R
% Ser:
0
24
16
0
0
16
0
16
8
0
8
8
0
0
39
% S
% Thr:
0
0
0
8
0
0
0
16
16
0
0
8
8
0
0
% T
% Val:
0
0
0
8
0
8
0
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
16
0
0
8
0
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _