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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPPL2
All Species:
14.85
Human Site:
Y344
Identified Species:
27.22
UniProt:
P10696
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10696
NP_112603.2
532
57377
Y344
G
H
H
E
S
R
A
Y
R
A
L
T
E
T
I
Chimpanzee
Pan troglodytes
XP_001146156
534
57545
Y346
G
H
H
E
S
R
A
Y
R
A
L
T
E
T
I
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
K474
G
H
H
E
G
K
A
K
Q
A
L
H
E
A
V
Dog
Lupus familis
XP_534605
554
59751
Y347
G
H
H
D
G
T
A
Y
L
A
L
T
E
A
V
Cat
Felis silvestris
Mouse
Mus musculus
P24823
529
57193
Y343
G
H
H
E
T
V
A
Y
R
A
L
T
E
A
V
Rat
Rattus norvegicus
P15693
540
58384
Y345
G
H
H
A
G
T
A
Y
L
A
L
T
E
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
H340
G
R
I
D
H
G
H
H
E
G
K
A
K
Q
A
Frog
Xenopus laevis
NP_001091135
530
58155
K346
G
H
H
D
G
K
A
K
Q
A
L
T
E
G
V
Zebra Danio
Brachydanio rerio
NP_001020359
521
56944
K344
G
H
H
A
G
Q
A
K
Y
A
L
T
E
A
V
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
K349
G
H
H
E
G
K
A
K
Q
A
L
Y
E
A
V
Fruit Fly
Dros. melanogaster
Q24238
596
65244
R383
G
H
H
M
N
Y
A
R
A
A
L
H
E
L
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
K346
G
H
H
E
G
K
A
K
Q
A
L
H
E
A
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
A339
A
G
H
Q
N
D
P
A
S
Q
V
R
E
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
47.3
70.7
N.A.
73.8
72
N.A.
N.A.
56.2
59.9
56.2
54.3
40.2
N.A.
N.A.
N.A.
Protein Similarity:
100
94.3
59.2
79
N.A.
83.6
82.5
N.A.
N.A.
71
74.6
71.4
68.9
53.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
60
N.A.
73.3
60
N.A.
N.A.
6.6
53.3
53.3
53.3
46.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
73.3
N.A.
86.6
66.6
N.A.
N.A.
26.6
80
66.6
73.3
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
56.5
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
72.1
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
53.3
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
0
0
85
8
8
85
0
8
0
54
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
24
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
47
0
0
0
0
8
0
0
0
93
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
93
8
0
0
54
8
0
0
0
8
0
0
0
8
0
% G
% His:
0
85
93
0
8
0
8
8
0
0
0
24
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
16
% I
% Lys:
0
0
0
0
0
31
0
39
0
0
8
0
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
16
0
85
0
0
8
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
8
0
0
31
8
0
0
0
8
0
% Q
% Arg:
0
8
0
0
0
16
0
8
24
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
16
0
0
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
16
0
0
0
0
0
54
0
16
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
8
0
0
8
62
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
39
8
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _