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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIT
All Species:
10
Human Site:
S741
Identified Species:
22
UniProt:
P10721
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10721
NP_000213.1
976
109865
S741
T
K
A
D
K
R
R
S
V
R
I
G
S
Y
I
Chimpanzee
Pan troglodytes
XP_517285
1073
120068
S838
T
K
A
D
K
R
R
S
A
R
I
G
S
Y
I
Rhesus Macaque
Macaca mulatta
XP_001089071
976
109748
S741
T
K
A
D
K
R
R
S
A
R
I
G
S
Y
I
Dog
Lupus familis
XP_546306
967
107148
S731
R
P
V
S
T
S
S
S
N
D
S
F
S
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
P05532
975
108983
A740
K
T
D
K
R
R
S
A
R
I
D
S
Y
I
E
Rat
Rattus norvegicus
Q00495
978
109246
S732
R
P
V
S
T
S
S
S
D
S
F
F
K
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506832
966
107509
A731
K
A
G
K
R
R
S
A
G
A
G
S
Y
A
E
Chicken
Gallus gallus
Q08156
960
107293
V727
K
A
D
K
K
R
P
V
K
S
G
S
Y
T
D
Frog
Xenopus laevis
Q91909
954
106841
K725
V
V
P
T
K
T
D
K
R
R
S
G
S
F
G
Zebra Danio
Brachydanio rerio
Q8JFR5
976
109261
Y732
S
L
N
K
G
D
S
Y
S
D
S
D
A
V
S
Tiger Blowfish
Takifugu rubipres
Q8AXC6
984
110714
R731
S
E
K
R
R
S
L
R
E
G
S
P
Y
V
E
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
98.3
40.4
N.A.
82.2
40.1
N.A.
66.5
65.9
56.2
48.5
46.3
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.4
99.2
57.2
N.A.
89.9
58.1
N.A.
77.9
78.3
71.4
65.3
62.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
13.3
N.A.
6.6
6.6
N.A.
6.6
13.3
26.6
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
13.3
N.A.
20
6.6
N.A.
20
13.3
33.3
13.3
20
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
28
0
0
0
0
19
19
10
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
28
0
10
10
0
10
19
10
10
0
0
19
% D
% Glu:
0
10
0
0
0
0
0
0
10
0
0
0
0
10
28
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
19
0
10
0
% F
% Gly:
0
0
10
0
10
0
0
0
10
10
19
37
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
28
0
0
10
28
% I
% Lys:
28
28
10
37
46
0
0
10
10
0
0
0
10
0
0
% K
% Leu:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
19
10
0
0
0
10
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% Q
% Arg:
19
0
0
10
28
55
28
10
19
37
0
0
0
0
0
% R
% Ser:
19
0
0
19
0
28
46
46
10
19
37
28
46
0
10
% S
% Thr:
28
10
0
10
19
10
0
0
0
0
0
0
0
10
0
% T
% Val:
10
10
19
0
0
0
0
10
10
0
0
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
37
28
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _