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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIT All Species: 40
Human Site: T574 Identified Species: 88
UniProt: P10721 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10721 NP_000213.1 976 109865 T574 N Y V Y I D P T Q L P Y D H K
Chimpanzee Pan troglodytes XP_517285 1073 120068 T671 N Y V Y I D P T Q L P Y D H K
Rhesus Macaque Macaca mulatta XP_001089071 976 109748 T574 N Y V Y I D P T Q L P Y D H K
Dog Lupus familis XP_546306 967 107148 T564 S Y T F I D P T Q L P Y N E K
Cat Felis silvestris
Mouse Mus musculus P05532 975 108983 T573 N Y V Y I D P T Q L P Y D H K
Rat Rattus norvegicus Q00495 978 109246 T565 S Y T F I D P T Q L P Y N E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506832 966 107509 T564 S Y V Y I D P T Q L P Y D H K
Chicken Gallus gallus Q08156 960 107293 T560 N Y V Y I D P T Q L P Y D H K
Frog Xenopus laevis Q91909 954 106841 Y558 I N G N N Y V Y I D P T Q L P
Zebra Danio Brachydanio rerio Q8JFR5 976 109261 T565 N Y V Y I D P T Q L P Y D H Q
Tiger Blowfish Takifugu rubipres Q8AXC6 984 110714 T564 N Y V Y I D P T Q L P Y D H Q
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.3 98.3 40.4 N.A. 82.2 40.1 N.A. 66.5 65.9 56.2 48.5 46.3 N.A. N.A. N.A. N.A.
Protein Similarity: 100 90.4 99.2 57.2 N.A. 89.9 58.1 N.A. 77.9 78.3 71.4 65.3 62.6 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 66.6 N.A. 100 66.6 N.A. 93.3 100 6.6 93.3 93.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 100 86.6 N.A. 100 100 6.6 100 100 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 91 0 0 0 10 0 0 73 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 % E
% Phe: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 73 0 % H
% Ile: 10 0 0 0 91 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73 % K
% Leu: 0 0 0 0 0 0 0 0 0 91 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 64 10 0 10 10 0 0 0 0 0 0 0 19 0 0 % N
% Pro: 0 0 0 0 0 0 91 0 0 0 100 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 91 0 0 0 10 0 19 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 28 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 19 0 0 0 0 91 0 0 0 10 0 0 0 % T
% Val: 0 0 73 0 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 91 0 73 0 10 0 10 0 0 0 91 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _