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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UROS
All Species:
16.06
Human Site:
S45
Identified Species:
50.48
UniProt:
P10746
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10746
NP_000366.1
265
28628
S45
F
E
F
L
S
L
P
S
F
S
E
K
L
S
H
Chimpanzee
Pan troglodytes
XP_508102
265
28641
S45
F
E
F
L
S
L
P
S
F
S
E
K
L
S
H
Rhesus Macaque
Macaca mulatta
XP_001086303
265
28634
S45
F
E
F
L
S
L
P
S
F
S
E
K
L
S
H
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P51163
265
28485
S45
F
E
F
M
S
L
P
S
L
S
E
K
L
S
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572507
277
30877
E47
F
G
F
K
N
L
D
E
L
R
A
K
L
Q
N
Honey Bee
Apis mellifera
XP_392378
266
29625
E50
F
E
F
V
N
I
S
E
L
R
T
C
F
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791243
313
34446
T44
F
E
F
I
D
L
D
T
L
Y
A
H
I
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06174
275
30893
V51
V
I
Q
D
F
R
N
V
L
N
T
I
P
N
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.1
N.A.
N.A.
77.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
31.4
33
N.A.
33.2
Protein Similarity:
100
100
99.6
N.A.
N.A.
87.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
45.4
50
N.A.
49.5
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
20
N.A.
40
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
40
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% C
% Asp:
0
0
0
13
13
0
25
0
0
0
0
0
0
0
0
% D
% Glu:
0
75
0
0
0
0
0
25
0
0
50
0
0
0
0
% E
% Phe:
88
0
88
0
13
0
0
0
38
0
0
0
13
0
0
% F
% Gly:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
63
% H
% Ile:
0
13
0
13
0
13
0
0
0
0
0
13
13
0
0
% I
% Lys:
0
0
0
13
0
0
0
0
0
0
0
63
0
0
0
% K
% Leu:
0
0
0
38
0
75
0
0
63
0
0
0
63
13
0
% L
% Met:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
25
0
13
0
0
13
0
0
0
13
13
% N
% Pro:
0
0
0
0
0
0
50
0
0
0
0
0
13
0
0
% P
% Gln:
0
0
13
0
0
0
0
0
0
0
0
0
0
13
0
% Q
% Arg:
0
0
0
0
0
13
0
0
0
25
0
0
0
0
0
% R
% Ser:
0
0
0
0
50
0
13
50
0
50
0
0
0
63
13
% S
% Thr:
0
0
0
0
0
0
0
13
0
0
25
0
0
0
0
% T
% Val:
13
0
0
13
0
0
0
13
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _