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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UROS All Species: 16.06
Human Site: S47 Identified Species: 50.48
UniProt: P10746 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10746 NP_000366.1 265 28628 S47 F L S L P S F S E K L S H P E
Chimpanzee Pan troglodytes XP_508102 265 28641 S47 F L S L P S F S E K L S H P E
Rhesus Macaque Macaca mulatta XP_001086303 265 28634 S47 F L S L P S F S E K L S H P E
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P51163 265 28485 S47 F M S L P S L S E K L S H P E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572507 277 30877 R49 F K N L D E L R A K L Q N P D
Honey Bee Apis mellifera XP_392378 266 29625 R52 F V N I S E L R T C F L S S S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791243 313 34446 Y46 F I D L D T L Y A H I S H P E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P06174 275 30893 N53 Q D F R N V L N T I P N Y L N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.1 N.A. N.A. 77.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 31.4 33 N.A. 33.2
Protein Similarity: 100 100 99.6 N.A. N.A. 87.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 45.4 50 N.A. 49.5
P-Site Identity: 100 100 100 N.A. N.A. 86.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 33.3 6.6 N.A. 40
P-Site Similarity: 100 100 100 N.A. N.A. 93.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 53.3 26.6 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % C
% Asp: 0 13 13 0 25 0 0 0 0 0 0 0 0 0 13 % D
% Glu: 0 0 0 0 0 25 0 0 50 0 0 0 0 0 63 % E
% Phe: 88 0 13 0 0 0 38 0 0 0 13 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 13 0 0 63 0 0 % H
% Ile: 0 13 0 13 0 0 0 0 0 13 13 0 0 0 0 % I
% Lys: 0 13 0 0 0 0 0 0 0 63 0 0 0 0 0 % K
% Leu: 0 38 0 75 0 0 63 0 0 0 63 13 0 13 0 % L
% Met: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 25 0 13 0 0 13 0 0 0 13 13 0 13 % N
% Pro: 0 0 0 0 50 0 0 0 0 0 13 0 0 75 0 % P
% Gln: 13 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % Q
% Arg: 0 0 0 13 0 0 0 25 0 0 0 0 0 0 0 % R
% Ser: 0 0 50 0 13 50 0 50 0 0 0 63 13 13 13 % S
% Thr: 0 0 0 0 0 13 0 0 25 0 0 0 0 0 0 % T
% Val: 0 13 0 0 0 13 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 13 0 0 0 0 13 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _