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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UROS
All Species:
15.76
Human Site:
T247
Identified Species:
49.52
UniProt:
P10746
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10746
NP_000366.1
265
28628
T247
S
C
T
A
E
S
P
T
P
Q
A
L
A
T
G
Chimpanzee
Pan troglodytes
XP_508102
265
28641
T247
S
C
T
A
E
S
P
T
P
Q
A
L
A
T
G
Rhesus Macaque
Macaca mulatta
XP_001086303
265
28634
T247
S
C
T
A
E
S
P
T
P
Q
A
L
A
T
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P51163
265
28485
T247
S
C
T
A
E
S
P
T
P
Q
A
L
A
A
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572507
277
30877
T245
Y
C
T
A
E
R
P
T
V
E
H
L
V
K
V
Honey Bee
Apis mellifera
XP_392378
266
29625
D245
F
A
T
A
N
K
P
D
P
V
S
L
L
D
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791243
313
34446
P297
G
V
A
E
K
P
N
P
T
A
L
L
Q
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06174
275
30893
D260
D
V
V
S
P
K
P
D
P
K
S
L
L
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.1
N.A.
N.A.
77.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
31.4
33
N.A.
33.2
Protein Similarity:
100
100
99.6
N.A.
N.A.
87.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
45.4
50
N.A.
49.5
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
33.3
N.A.
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
13
75
0
0
0
0
0
13
50
0
50
25
25
% A
% Cys:
0
63
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
0
0
0
25
0
0
0
0
0
25
0
% D
% Glu:
0
0
0
13
63
0
0
0
0
13
0
0
0
0
0
% E
% Phe:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% I
% Lys:
0
0
0
0
13
25
0
0
0
13
0
0
0
13
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
13
100
25
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
13
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
13
13
88
13
75
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
50
0
0
13
0
0
% Q
% Arg:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% R
% Ser:
50
0
0
13
0
50
0
0
0
0
25
0
0
0
0
% S
% Thr:
0
0
75
0
0
0
0
63
13
0
0
0
0
38
0
% T
% Val:
0
25
13
0
0
0
0
0
13
13
0
0
13
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _