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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ESD All Species: 46.97
Human Site: S96 Identified Species: 79.49
UniProt: P10768 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10768 NP_001975.1 282 31463 S96 N I K G E D E S W D F G T G A
Chimpanzee Pan troglodytes XP_001150093 316 35212 S130 N I K G E D E S W D F G T G A
Rhesus Macaque Macaca mulatta XP_001097371 259 28732 S96 N I K G E D E S W D F G T G A
Dog Lupus familis XP_848369 282 31374 S96 N I K G E D D S W D F G T G A
Cat Felis silvestris
Mouse Mus musculus Q9R0P3 282 31301 S96 N I K G E D D S W D F G T G A
Rat Rattus norvegicus B0BNE5 282 31345 S96 N I K G E D D S W D F G T G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513718 282 31435 S96 N I K G E D E S W D F G S G A
Chicken Gallus gallus
Frog Xenopus laevis NP_001087760 282 31523 S96 N I D G E E E S W D F G T G A
Zebra Danio Brachydanio rerio NP_001017796 282 31153 S96 N I E G E E E S W D F G T G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_732486 330 36334 A141 E I A G Q D D A Y D F G S G A
Honey Bee Apis mellifera XP_395656 286 32137 D97 N I L G E D D D W D F G T G A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198332 281 31170 S97 S I E G E D E S Y D F G S G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LAS8 284 31637 S99 N V E G E A D S Y D F G V G A
Baker's Yeast Sacchar. cerevisiae P40363 299 33916 S101 V A N D P E G S W D F G Q G A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.9 90 96.4 N.A. 91.8 91.1 N.A. 88.3 N.A. 81.2 80.5 N.A. 50.9 65.7 N.A. 60.6
Protein Similarity: 100 88.9 91.1 98.5 N.A. 96.4 95.7 N.A. 95 N.A. 89.7 91.4 N.A. 63.9 78.3 N.A. 77.3
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 93.3 N.A. 86.6 86.6 N.A. 53.3 80 N.A. 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 N.A. 93.3 100 N.A. 86.6 86.6 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. 56.6 39.8 N.A.
Protein Similarity: N.A. N.A. N.A. 71.8 58.1 N.A.
P-Site Identity: N.A. N.A. N.A. 60 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 8 0 8 0 0 0 0 0 0 100 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 0 72 43 8 0 100 0 0 0 0 0 % D
% Glu: 8 0 22 0 86 22 50 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % F
% Gly: 0 0 0 93 0 0 8 0 0 0 0 100 0 100 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 86 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 79 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 0 0 0 0 0 0 86 0 0 0 0 22 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 65 0 0 % T
% Val: 8 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 79 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 22 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _