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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESD
All Species:
44.24
Human Site:
Y191
Identified Species:
74.87
UniProt:
P10768
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10768
NP_001975.1
282
31463
Y191
G
K
K
A
F
S
G
Y
L
G
T
D
Q
S
K
Chimpanzee
Pan troglodytes
XP_001150093
316
35212
Y225
G
K
K
A
F
S
G
Y
L
G
T
D
Q
S
K
Rhesus Macaque
Macaca mulatta
XP_001097371
259
28732
P182
I
C
N
P
V
L
C
P
W
G
K
K
A
F
S
Dog
Lupus familis
XP_848369
282
31374
Y191
G
K
K
A
F
G
G
Y
L
G
T
D
Q
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0P3
282
31301
Y191
G
K
K
A
F
S
G
Y
L
G
P
D
E
S
K
Rat
Rattus norvegicus
B0BNE5
282
31345
Y191
G
K
K
A
F
N
G
Y
L
G
P
D
Q
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513718
282
31435
Y191
G
K
K
A
F
A
G
Y
L
G
S
D
Q
G
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087760
282
31523
Y191
G
Q
K
A
F
S
G
Y
L
G
P
D
T
G
K
Zebra Danio
Brachydanio rerio
NP_001017796
282
31153
Y191
G
Q
K
A
F
S
G
Y
L
G
S
D
K
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732486
330
36334
Y236
G
K
K
A
F
A
G
Y
L
G
S
N
P
D
D
Honey Bee
Apis mellifera
XP_395656
286
32137
G195
A
F
T
G
Y
L
G
G
L
E
T
N
V
E
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198332
281
31170
Y192
G
Q
K
A
F
K
G
Y
L
G
P
D
E
N
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LAS8
284
31637
Y194
G
Q
K
A
F
T
N
Y
L
G
D
N
K
A
A
Baker's Yeast
Sacchar. cerevisiae
P40363
299
33916
Y205
G
Q
K
A
F
K
G
Y
L
G
E
E
K
A
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
90
96.4
N.A.
91.8
91.1
N.A.
88.3
N.A.
81.2
80.5
N.A.
50.9
65.7
N.A.
60.6
Protein Similarity:
100
88.9
91.1
98.5
N.A.
96.4
95.7
N.A.
95
N.A.
89.7
91.4
N.A.
63.9
78.3
N.A.
77.3
P-Site Identity:
100
100
6.6
93.3
N.A.
86.6
86.6
N.A.
80
N.A.
73.3
73.3
N.A.
60
20
N.A.
60
P-Site Similarity:
100
100
6.6
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
80
93.3
N.A.
80
33.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.6
39.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
71.8
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
86
0
15
0
0
0
0
0
0
8
15
8
% A
% Cys:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
65
0
8
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
8
8
15
8
0
% E
% Phe:
0
8
0
0
86
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
86
0
0
8
0
8
86
8
0
93
0
0
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
50
86
0
0
15
0
0
0
0
8
8
22
0
50
% K
% Leu:
0
0
0
0
0
15
0
0
93
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
8
0
0
0
0
22
0
8
0
% N
% Pro:
0
0
0
8
0
0
0
8
0
0
29
0
8
0
0
% P
% Gln:
0
36
0
0
0
0
0
0
0
0
0
0
36
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
36
0
0
0
0
22
0
0
43
8
% S
% Thr:
0
0
8
0
0
8
0
0
0
0
29
0
8
0
22
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _