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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESD
All Species:
43.64
Human Site:
Y258
Identified Species:
73.85
UniProt:
P10768
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10768
NP_001975.1
282
31463
Y258
V
F
R
L
Q
E
G
Y
D
H
S
Y
Y
F
I
Chimpanzee
Pan troglodytes
XP_001150093
316
35212
Y292
V
F
R
L
Q
E
G
Y
D
H
S
Y
Y
F
I
Rhesus Macaque
Macaca mulatta
XP_001097371
259
28732
P236
L
L
D
G
Q
L
L
P
D
N
F
I
A
A
C
Dog
Lupus familis
XP_848369
282
31374
Y258
V
F
R
L
Q
E
G
Y
D
H
S
Y
Y
F
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0P3
282
31301
Y258
V
F
R
L
Q
E
G
Y
D
H
S
Y
Y
F
I
Rat
Rattus norvegicus
B0BNE5
282
31345
Y258
V
F
R
L
Q
E
G
Y
D
H
S
Y
Y
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513718
282
31435
Y258
V
F
R
L
Q
E
G
Y
D
H
S
Y
F
F
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087760
282
31523
Y258
V
F
R
L
Q
E
G
Y
D
H
S
Y
F
F
I
Zebra Danio
Brachydanio rerio
NP_001017796
282
31153
Y258
V
F
R
L
Q
Q
G
Y
D
H
S
Y
Y
F
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732486
330
36334
Y304
I
F
K
Q
R
E
G
Y
D
H
S
Y
F
Y
I
Honey Bee
Apis mellifera
XP_395656
286
32137
Y262
V
L
R
F
Q
E
G
Y
D
H
S
Y
F
F
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198332
281
31170
C244
P
E
N
F
V
T
S
C
Q
V
S
R
T
G
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LAS8
284
31637
Y260
L
L
R
L
H
P
G
Y
D
H
S
Y
Y
F
I
Baker's Yeast
Sacchar. cerevisiae
P40363
299
33916
F274
E
I
K
K
V
H
G
F
D
H
S
Y
Y
F
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
90
96.4
N.A.
91.8
91.1
N.A.
88.3
N.A.
81.2
80.5
N.A.
50.9
65.7
N.A.
60.6
Protein Similarity:
100
88.9
91.1
98.5
N.A.
96.4
95.7
N.A.
95
N.A.
89.7
91.4
N.A.
63.9
78.3
N.A.
77.3
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
60
80
N.A.
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
100
N.A.
100
100
N.A.
93.3
86.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.6
39.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
71.8
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
15
% C
% Asp:
0
0
8
0
0
0
0
0
93
0
0
0
0
0
0
% D
% Glu:
8
8
0
0
0
65
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
65
0
15
0
0
0
8
0
0
8
0
29
79
0
% F
% Gly:
0
0
0
8
0
0
86
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
8
8
0
0
0
86
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
0
0
0
8
0
0
79
% I
% Lys:
0
0
15
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
15
22
0
65
0
8
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
72
8
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
72
0
8
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
0
0
0
93
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% T
% Val:
65
0
0
0
15
0
0
0
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
79
0
0
0
86
58
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _