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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPD1 All Species: 56.06
Human Site: S247 Identified Species: 82.22
UniProt: P10809 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10809 NP_002147.2 573 61055 S247 Q D A Y V L L S E K K I S S I
Chimpanzee Pan troglodytes XP_001169030 573 61022 S247 Q D A Y V L L S E K K I S S V
Rhesus Macaque Macaca mulatta XP_001082397 576 61283 S247 Q D A Y V L L S E K K I S S V
Dog Lupus familis XP_536016 573 60977 S247 Q D A Y V L L S E K K I S S V
Cat Felis silvestris
Mouse Mus musculus NP_034607 573 60937 S247 Q D A Y V L L S E K K I S S V
Rat Rattus norvegicus P63039 573 60937 S247 Q D A Y V L L S E K K I S S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZL72 573 60954 S247 Q D A Y V L I S E K K I S S V
Frog Xenopus laevis NP_001083970 579 61616 S247 Q D A Y L L L S E K K I S S V
Zebra Danio Brachydanio rerio NP_851847 575 61178 S247 Q D A Y V L L S E K K I S S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O02649 573 60790 S243 Q D A L L L L S E K K I S S V
Honey Bee Apis mellifera XP_392899 570 60394 S242 Q D A L L L F S E K K I S S V
Nematode Worm Caenorhab. elegans P50140 568 60082 S238 E K A L V L L S E K K I S Q V
Sea Urchin Strong. purpuratus XP_795205 586 62222 S253 Q D A L L L L S E K K I S T I
Poplar Tree Populus trichocarpa
Maize Zea mays Q43298 576 60917 H256 E D P L I L I H D K K V T N M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P29197 577 61262 H253 D D P L I L I H E K K I S S I
Baker's Yeast Sacchar. cerevisiae P19882 572 60733 S244 E K P L L L L S E K K I S S I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.5 98 N.A. 97.5 97.5 N.A. N.A. 94 89.4 87.3 N.A. 74 74.6 71 74.9
Protein Similarity: 100 100 98.7 98.9 N.A. 98.2 98.2 N.A. N.A. 97.7 94.9 94.4 N.A. 86.3 86 82.3 87.3
P-Site Identity: 100 93.3 93.3 93.3 N.A. 93.3 93.3 N.A. N.A. 86.6 86.6 93.3 N.A. 80 73.3 66.6 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 93.3 86.6 80 93.3
Percent
Protein Identity: N.A. 58.3 N.A. 57.8 55.6 N.A.
Protein Similarity: N.A. 76.9 N.A. 76.4 73.3 N.A.
P-Site Identity: N.A. 26.6 N.A. 60 66.6 N.A.
P-Site Similarity: N.A. 80 N.A. 73.3 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 82 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 88 0 0 0 0 0 0 7 0 0 0 0 0 0 % D
% Glu: 19 0 0 0 0 0 0 0 94 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 13 0 19 0 0 0 0 94 0 0 25 % I
% Lys: 0 13 0 0 0 0 0 0 0 100 100 0 0 0 0 % K
% Leu: 0 0 0 44 32 100 75 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % N
% Pro: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 75 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 88 0 0 0 0 94 82 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % T
% Val: 0 0 0 0 57 0 0 0 0 0 0 7 0 0 69 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 57 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _