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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPD1
All Species:
35.76
Human Site:
S497
Identified Species:
52.44
UniProt:
P10809
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10809
NP_002147.2
573
61055
S497
I
V
E
K
I
M
Q
S
S
S
E
V
G
Y
D
Chimpanzee
Pan troglodytes
XP_001169030
573
61022
S497
I
V
E
K
I
M
Q
S
S
S
E
V
G
Y
D
Rhesus Macaque
Macaca mulatta
XP_001082397
576
61283
S497
I
V
E
K
I
M
Q
S
S
S
E
V
G
Y
D
Dog
Lupus familis
XP_536016
573
60977
S497
I
V
E
K
I
M
Q
S
S
S
E
V
G
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
NP_034607
573
60937
S497
I
V
E
K
I
L
Q
S
S
S
E
V
G
Y
D
Rat
Rattus norvegicus
P63039
573
60937
S497
I
V
E
K
I
L
Q
S
S
S
E
V
G
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL72
573
60954
S497
I
V
E
K
I
L
Q
S
S
S
E
V
G
Y
D
Frog
Xenopus laevis
NP_001083970
579
61616
S497
V
V
E
K
I
I
Q
S
P
V
E
I
G
Y
D
Zebra Danio
Brachydanio rerio
NP_851847
575
61178
S497
V
V
E
K
I
L
Q
S
S
T
E
I
G
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02649
573
60790
Q493
V
V
A
K
V
E
N
Q
A
G
D
Y
G
Y
D
Honey Bee
Apis mellifera
XP_392899
570
60394
G492
V
V
A
K
V
S
D
G
N
L
G
Y
D
A
L
Nematode Worm
Caenorhab. elegans
P50140
568
60082
N488
I
I
D
E
V
T
G
N
S
N
T
S
Y
G
Y
Sea Urchin
Strong. purpuratus
XP_795205
586
62222
A503
I
V
E
K
V
I
E
A
S
E
E
I
G
Y
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43298
576
60917
Q505
V
V
G
K
L
L
E
Q
G
N
T
D
L
G
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P29197
577
61262
Q502
I
V
G
K
L
L
E
Q
D
N
P
D
L
G
Y
Baker's Yeast
Sacchar. cerevisiae
P19882
572
60733
E494
I
I
G
K
L
I
D
E
Y
G
D
D
F
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
98
N.A.
97.5
97.5
N.A.
N.A.
94
89.4
87.3
N.A.
74
74.6
71
74.9
Protein Similarity:
100
100
98.7
98.9
N.A.
98.2
98.2
N.A.
N.A.
97.7
94.9
94.4
N.A.
86.3
86
82.3
87.3
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
66.6
73.3
N.A.
33.3
13.3
13.3
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
86.6
100
N.A.
60
33.3
53.3
93.3
Percent
Protein Identity:
N.A.
58.3
N.A.
57.8
55.6
N.A.
Protein Similarity:
N.A.
76.9
N.A.
76.4
73.3
N.A.
P-Site Identity:
N.A.
13.3
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
0
0
7
7
0
0
0
0
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
13
0
7
0
13
19
7
0
63
% D
% Glu:
0
0
63
7
0
7
19
7
0
7
63
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
19
0
0
0
7
7
7
13
7
0
69
19
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
69
13
0
0
57
19
0
0
0
0
0
19
0
0
0
% I
% Lys:
0
0
0
94
0
0
0
0
0
0
0
0
0
0
7
% K
% Leu:
0
0
0
0
19
38
0
0
0
7
0
0
13
0
7
% L
% Met:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
7
7
19
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
57
19
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
0
57
63
44
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
7
0
0
0
7
13
0
0
0
0
% T
% Val:
32
88
0
0
25
0
0
0
0
7
0
44
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
13
7
69
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _