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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THRB
All Species:
22.73
Human Site:
Y171
Identified Species:
55.56
UniProt:
P10828
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10828
NP_000452.2
461
52788
Y171
C
R
F
K
K
C
I
Y
V
G
M
A
T
D
L
Chimpanzee
Pan troglodytes
XP_001163991
467
53531
Y177
C
R
F
K
K
C
I
Y
V
G
M
A
T
D
L
Rhesus Macaque
Macaca mulatta
XP_001090554
461
52739
Y171
C
R
F
K
K
C
I
Y
V
G
M
A
T
D
L
Dog
Lupus familis
XP_862690
467
53497
Y177
C
R
F
K
K
C
I
Y
V
G
M
A
T
D
L
Cat
Felis silvestris
Mouse
Mus musculus
P37242
461
52611
Y171
C
R
F
K
K
C
I
Y
V
G
M
A
T
D
L
Rat
Rattus norvegicus
P18113
461
52637
Y171
C
R
F
K
K
C
I
Y
V
G
M
A
T
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P04625
408
46739
I166
S
A
E
E
W
E
L
I
H
V
V
T
E
A
H
Frog
Xenopus laevis
P18117
373
42282
I134
T
Q
E
E
W
E
L
I
Q
V
V
T
E
A
H
Zebra Danio
Brachydanio rerio
Q9PVE4
395
45137
A156
V
V
T
E
A
H
M
A
T
N
A
Q
G
N
H
Tiger Blowfish
Takifugu rubipres
Q9W5Z3
447
49514
A186
M
I
N
R
V
R
K
A
H
Q
E
T
F
P
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
99.7
96.3
N.A.
96.5
95.8
N.A.
N.A.
72.6
76.1
75
33.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.8
99.7
97.2
N.A.
97.6
96.9
N.A.
N.A.
79.6
78.5
79.8
49.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
0
0
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
26.6
20
6.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
0
20
0
0
10
60
0
20
0
% A
% Cys:
60
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% D
% Glu:
0
0
20
30
0
20
0
0
0
0
10
0
20
0
0
% E
% Phe:
0
0
60
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
60
0
0
10
0
0
% G
% His:
0
0
0
0
0
10
0
0
20
0
0
0
0
0
30
% H
% Ile:
0
10
0
0
0
0
60
20
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
60
60
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
60
% L
% Met:
10
0
0
0
0
0
10
0
0
0
60
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
10
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
10
0
0
0
0
0
0
10
10
0
10
0
0
0
% Q
% Arg:
0
60
0
10
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
10
0
10
0
0
0
0
0
10
0
0
30
60
0
0
% T
% Val:
10
10
0
0
10
0
0
0
60
20
20
0
0
0
0
% V
% Trp:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _