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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLU
All Species:
5.45
Human Site:
S185
Identified Species:
17.14
UniProt:
P10909
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10909
NP_001822.2
449
52495
S185
D
H
F
S
R
A
S
S
I
I
D
E
L
F
Q
Chimpanzee
Pan troglodytes
XP_519677
501
57732
S237
D
H
F
S
R
A
S
S
I
M
D
E
L
F
Q
Rhesus Macaque
Macaca mulatta
XP_001087629
531
60963
T253
E
D
V
F
S
Q
L
T
V
D
V
N
S
L
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q06890
448
51637
G184
D
S
F
A
R
A
S
G
I
I
D
T
L
F
Q
Rat
Rattus norvegicus
P05371
447
51357
G184
D
S
F
T
R
A
S
G
I
I
D
T
L
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515556
554
63100
Q196
E
N
F
S
L
M
E
Q
S
I
D
D
L
F
Q
Chicken
Gallus gallus
NP_990231
448
51330
D189
G
V
E
D
I
F
Q
D
S
T
Q
L
Y
G
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957096
448
51743
D182
E
S
Y
T
E
V
S
D
G
V
E
N
M
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
22.9
N.A.
N.A.
76.3
76.8
N.A.
41.5
46.7
N.A.
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
89.2
42.3
N.A.
N.A.
87.5
87.7
N.A.
58.1
68.1
N.A.
60.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
0
N.A.
N.A.
73.3
73.3
N.A.
46.6
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
N.A.
N.A.
80
80
N.A.
66.6
0
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
50
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
13
0
13
0
0
0
25
0
13
63
13
0
0
0
% D
% Glu:
38
0
13
0
13
0
13
0
0
0
13
25
0
0
0
% E
% Phe:
0
0
63
13
0
13
0
0
0
0
0
0
0
75
13
% F
% Gly:
13
0
0
0
0
0
0
25
13
0
0
0
0
13
0
% G
% His:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
13
0
0
0
50
50
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
13
0
13
0
0
0
0
13
63
13
0
% L
% Met:
0
0
0
0
0
13
0
0
0
13
0
0
13
0
0
% M
% Asn:
0
13
0
0
0
0
0
0
0
0
0
25
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% P
% Gln:
0
0
0
0
0
13
13
13
0
0
13
0
0
0
63
% Q
% Arg:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
38
0
38
13
0
63
25
25
0
0
0
13
0
0
% S
% Thr:
0
0
0
25
0
0
0
13
0
13
0
25
0
0
13
% T
% Val:
0
13
13
0
0
13
0
0
13
13
13
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
0
0
0
0
0
0
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _