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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GHR All Species: 18.48
Human Site: S597 Identified Species: 40.67
UniProt: P10912 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10912 NP_000154.1 638 71500 S597 M P V P D Y T S I H I V Q S P
Chimpanzee Pan troglodytes XP_526938 638 71482 S597 M P V P D Y T S I H I V Q S P
Rhesus Macaque Macaca mulatta P79194 638 71309 S597 M P V P D Y T S I H I V Q S P
Dog Lupus familis XP_536502 677 75573 N623 V Q E P R A Q N L A S F E E P
Cat Felis silvestris
Mouse Mus musculus P16882 650 72765 T608 M S V P D Y T T V H T V Q S P
Rat Rattus norvegicus P16310 638 71218 V597 P V P D Y T T V H T V K S P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515848 345 39705 I305 F L V I I L G I F G L T V V F
Chicken Gallus gallus Q02092 608 68554 S567 M P V P D Y T S I H I V H S P
Frog Xenopus laevis NP_001081978 603 67604 T563 D M P V S D Y T S V H I I N S
Zebra Danio Brachydanio rerio NP_001077047 570 64111 P530 S V N D S Q T P Y L L L E P P
Tiger Blowfish Takifugu rubipres NP_001072093 510 57234 Y470 H T S C Q E K Y Y T D C E R L
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 94.1 24 N.A. 68 69.9 N.A. 30.8 58.6 45.7 35.5 24.7 N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.3 96.5 38.8 N.A. 78.9 81 N.A. 38.4 71.3 64.5 51.7 42.3 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 73.3 6.6 N.A. 6.6 93.3 0 13.3 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 40 N.A. 86.6 13.3 N.A. 13.3 93.3 20 33.3 6.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 10 0 0 19 46 10 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 10 0 0 10 0 0 0 0 0 0 28 10 0 % E
% Phe: 10 0 0 0 0 0 0 0 10 0 0 10 0 0 10 % F
% Gly: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 10 46 10 0 10 0 0 % H
% Ile: 0 0 0 10 10 0 0 10 37 0 37 10 10 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % K
% Leu: 0 10 0 0 0 10 0 0 10 10 19 10 0 0 10 % L
% Met: 46 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 10 0 0 0 0 0 10 0 % N
% Pro: 10 37 19 55 0 0 0 10 0 0 0 0 0 19 64 % P
% Gln: 0 10 0 0 10 10 10 0 0 0 0 0 37 0 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 10 % R
% Ser: 10 10 10 0 19 0 0 37 10 0 10 0 10 46 10 % S
% Thr: 0 10 0 0 0 10 64 19 0 19 10 10 0 0 0 % T
% Val: 10 19 55 10 0 0 0 10 10 10 10 46 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 46 10 10 19 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _