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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF1
All Species:
19.09
Human Site:
S267
Identified Species:
46.67
UniProt:
P10914
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10914
NP_002189.1
325
36502
S267
E
P
G
V
Q
P
T
S
V
Y
G
D
F
S
C
Chimpanzee
Pan troglodytes
XP_001150404
404
44443
S346
E
P
G
V
Q
P
T
S
V
Y
G
D
F
S
C
Rhesus Macaque
Macaca mulatta
XP_001104217
325
36454
S267
E
P
G
V
Q
P
T
S
V
Y
G
D
F
S
C
Dog
Lupus familis
XP_538621
321
35976
T263
Y
L
L
N
E
P
G
T
Q
P
P
S
L
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
P15314
329
37301
S268
E
P
G
T
Q
L
S
S
V
Y
G
D
F
S
C
Rat
Rattus norvegicus
P23570
328
37046
T268
E
P
G
A
Q
L
S
T
V
Y
G
D
F
S
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514327
318
36158
G260
G
Y
L
L
N
E
P
G
A
Q
T
I
Y
N
D
Chicken
Gallus gallus
Q90876
313
35991
Q242
I
K
L
L
E
P
T
Q
D
W
H
T
T
S
V
Frog
Xenopus laevis
NP_001085588
302
34021
S241
S
T
E
W
S
Q
T
S
V
D
G
K
G
F
F
Zebra Danio
Brachydanio rerio
NP_991310
287
32850
L230
Q
N
F
G
K
G
F
L
A
N
E
V
C
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.9
99
91.3
N.A.
84.5
84.4
N.A.
68.3
62.7
52.3
45.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
78.7
99.3
95.3
N.A.
92
91.4
N.A.
80.6
77.5
69.5
64
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
80
73.3
N.A.
0
20
26.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
86.6
86.6
N.A.
20
40
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
20
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
50
% C
% Asp:
0
0
0
0
0
0
0
0
10
10
0
50
0
0
10
% D
% Glu:
50
0
10
0
20
10
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
10
0
0
0
0
0
50
10
10
% F
% Gly:
10
0
50
10
0
10
10
10
0
0
60
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
10
0
0
10
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
10
30
20
0
20
0
10
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
10
0
0
0
0
10
0
0
0
10
0
% N
% Pro:
0
50
0
0
0
50
10
0
0
10
10
0
0
0
0
% P
% Gln:
10
0
0
0
50
10
0
10
10
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
10
0
20
50
0
0
0
10
0
60
0
% S
% Thr:
0
10
0
10
0
0
50
20
0
0
10
10
10
10
10
% T
% Val:
0
0
0
30
0
0
0
0
60
0
0
10
0
0
10
% V
% Trp:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
10
10
0
0
0
0
0
0
0
50
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _