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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYL2
All Species:
41.21
Human Site:
S131
Identified Species:
82.42
UniProt:
P10916
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10916
NP_000423.2
166
18789
S131
T
T
Q
A
E
R
F
S
K
E
E
V
D
Q
M
Chimpanzee
Pan troglodytes
XP_001144828
172
19212
L131
G
T
G
I
T
A
I
L
Q
I
G
K
L
R
P
Rhesus Macaque
Macaca mulatta
XP_001100796
166
18841
S131
T
T
Q
A
E
R
F
S
K
E
E
I
D
Q
M
Dog
Lupus familis
XP_850206
167
19006
S132
M
T
Q
A
D
R
F
S
E
E
E
V
K
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
P51667
166
18846
S131
T
T
Q
A
E
R
F
S
K
E
E
I
D
Q
M
Rat
Rattus norvegicus
P08733
166
18862
S131
T
T
Q
A
E
R
F
S
K
E
E
I
D
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506155
224
25391
S189
M
T
Q
A
E
R
F
S
Q
E
E
I
D
Q
M
Chicken
Gallus gallus
P02610
165
18687
S130
M
T
Q
E
G
R
F
S
Q
E
E
I
D
Q
M
Frog
Xenopus laevis
NP_001087308
167
19067
T131
M
T
Q
A
E
R
F
T
S
E
E
V
D
Q
M
Zebra Danio
Brachydanio rerio
NP_001035134
168
19100
S131
T
T
Q
A
D
R
F
S
P
E
E
M
E
Q
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40423
174
19936
T137
T
T
M
G
D
R
F
T
D
E
D
V
D
E
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09510
172
19922
S135
T
T
M
G
E
R
Y
S
E
E
Q
V
D
E
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
97.5
81.4
N.A.
96.3
95.7
N.A.
70.9
89.7
87.4
85.7
N.A.
52.2
N.A.
53.4
N.A.
Protein Similarity:
100
91.2
99.4
93.4
N.A.
97.5
97.5
N.A.
72.7
94.5
95.8
92.2
N.A.
68.9
N.A.
70.3
N.A.
P-Site Identity:
100
6.6
93.3
73.3
N.A.
93.3
93.3
N.A.
80
66.6
80
73.3
N.A.
53.3
N.A.
53.3
N.A.
P-Site Similarity:
100
20
100
86.6
N.A.
100
100
N.A.
93.3
80
86.6
93.3
N.A.
80
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
67
0
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
25
0
0
0
9
0
9
0
75
0
0
% D
% Glu:
0
0
0
9
59
0
0
0
17
92
75
0
9
17
0
% E
% Phe:
0
0
0
0
0
0
84
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
9
17
9
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
9
0
0
9
0
42
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
34
0
0
9
9
0
0
% K
% Leu:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
9
% L
% Met:
34
0
17
0
0
0
0
0
0
0
0
9
0
0
84
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% P
% Gln:
0
0
75
0
0
0
0
0
25
0
9
0
0
75
0
% Q
% Arg:
0
0
0
0
0
92
0
0
0
0
0
0
0
9
0
% R
% Ser:
0
0
0
0
0
0
0
75
9
0
0
0
0
0
0
% S
% Thr:
59
100
0
0
9
0
0
17
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
42
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _