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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYL2 All Species: 40
Human Site: T52 Identified Species: 80
UniProt: P10916 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10916 NP_000423.2 166 18789 T52 D K N D L R D T F A A L G R V
Chimpanzee Pan troglodytes XP_001144828 172 19212 T52 D K N D L R D T F A A L G R V
Rhesus Macaque Macaca mulatta XP_001100796 166 18841 T52 D K N D L R D T F A A L G R V
Dog Lupus familis XP_850206 167 19006 T53 D K E D L R D T F A A L G R I
Cat Felis silvestris
Mouse Mus musculus P51667 166 18846 T52 D K N D L R D T F A A L G R V
Rat Rattus norvegicus P08733 166 18862 T52 D K N D L R D T F A A L G R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506155 224 25391 T110 D K A D L R D T F A A L G R V
Chicken Gallus gallus P02610 165 18687 T52 D K A D L R D T F A A L G R L
Frog Xenopus laevis NP_001087308 167 19067 T52 D K D D L R D T F A A L G R L
Zebra Danio Brachydanio rerio NP_001035134 168 19100 T52 D K N D L R D T F A A L G R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40423 174 19936 M59 E K E D L H D M L A S L G K N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09510 172 19922 M55 D Q E D L K D M F A S L G K E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.9 97.5 81.4 N.A. 96.3 95.7 N.A. 70.9 89.7 87.4 85.7 N.A. 52.2 N.A. 53.4 N.A.
Protein Similarity: 100 91.2 99.4 93.4 N.A. 97.5 97.5 N.A. 72.7 94.5 95.8 92.2 N.A. 68.9 N.A. 70.3 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 100 100 N.A. 93.3 86.6 86.6 93.3 N.A. 46.6 N.A. 53.3 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 93.3 93.3 100 100 N.A. 66.6 N.A. 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 0 0 0 0 0 100 84 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 92 0 9 100 0 0 100 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 25 0 0 0 0 0 0 0 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 92 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % I
% Lys: 0 92 0 0 0 9 0 0 0 0 0 0 0 17 0 % K
% Leu: 0 0 0 0 100 0 0 0 9 0 0 100 0 0 25 % L
% Met: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % M
% Asn: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 84 0 0 0 0 0 0 0 84 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 84 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _