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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYL2
All Species:
27.88
Human Site:
Y118
Identified Species:
55.76
UniProt:
P10916
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10916
NP_000423.2
166
18789
Y118
K
G
V
L
K
A
D
Y
V
R
E
M
L
T
T
Chimpanzee
Pan troglodytes
XP_001144828
172
19212
Y118
K
G
V
L
K
A
D
Y
F
G
Q
L
V
G
T
Rhesus Macaque
Macaca mulatta
XP_001100796
166
18841
Y118
K
G
V
L
K
A
D
Y
V
R
D
M
L
T
T
Dog
Lupus familis
XP_850206
167
19006
F119
K
G
F
V
K
A
D
F
I
K
E
K
L
M
T
Cat
Felis silvestris
Mouse
Mus musculus
P51667
166
18846
Y118
K
G
S
L
K
A
D
Y
V
R
E
M
L
T
T
Rat
Rattus norvegicus
P08733
166
18862
Y118
K
G
S
L
K
A
D
Y
V
R
E
M
L
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506155
224
25391
Y176
K
G
V
L
K
S
D
Y
I
R
E
M
L
M
T
Chicken
Gallus gallus
P02610
165
18687
Y117
G
K
G
L
K
S
A
Y
I
K
E
M
L
M
T
Frog
Xenopus laevis
NP_001087308
167
19067
Y118
I
G
L
L
K
S
E
Y
I
R
E
M
L
M
T
Zebra Danio
Brachydanio rerio
NP_001035134
168
19100
F118
K
G
T
L
R
K
D
F
L
S
R
M
L
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40423
174
19936
R124
M
G
V
L
P
E
D
R
L
R
E
L
L
T
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09510
172
19922
H122
S
G
K
L
N
E
E
H
L
R
E
L
L
T
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
97.5
81.4
N.A.
96.3
95.7
N.A.
70.9
89.7
87.4
85.7
N.A.
52.2
N.A.
53.4
N.A.
Protein Similarity:
100
91.2
99.4
93.4
N.A.
97.5
97.5
N.A.
72.7
94.5
95.8
92.2
N.A.
68.9
N.A.
70.3
N.A.
P-Site Identity:
100
60
93.3
53.3
N.A.
93.3
93.3
N.A.
80
46.6
60
53.3
N.A.
60
N.A.
46.6
N.A.
P-Site Similarity:
100
80
100
80
N.A.
93.3
93.3
N.A.
93.3
66.6
86.6
73.3
N.A.
73.3
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
50
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
75
0
0
0
9
0
0
0
0
% D
% Glu:
0
0
0
0
0
17
17
0
0
0
75
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
17
9
0
0
0
0
0
0
% F
% Gly:
9
92
9
0
0
0
0
0
0
9
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% I
% Lys:
67
9
9
0
75
9
0
0
0
17
0
9
0
0
0
% K
% Leu:
0
0
9
92
0
0
0
0
25
0
0
25
92
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
67
0
34
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
9
0
67
9
0
0
0
0
% R
% Ser:
9
0
17
0
0
25
0
0
0
9
0
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
0
59
100
% T
% Val:
0
0
42
9
0
0
0
0
34
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _