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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IAPP
All Species:
4.55
Human Site:
T23
Identified Species:
20
UniProt:
P10997
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10997
NP_000406.1
89
9806
T23
A
L
N
H
L
K
A
T
P
I
E
S
H
Q
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001098180
89
9883
T23
A
L
N
H
L
K
A
T
P
I
E
S
H
Q
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P12968
93
10003
R27
H
L
R
A
T
P
V
R
S
G
S
N
P
Q
M
Rat
Rattus norvegicus
P12969
93
9996
G27
H
L
R
A
T
P
V
G
S
G
T
N
P
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P10286
125
13710
F23
V
V
C
Q
M
D
S
F
Q
A
A
P
V
R
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002661886
111
12347
L17
V
P
H
N
R
Y
S
L
P
S
I
E
R
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
N.A.
N.A.
64.5
64.5
N.A.
N.A.
20
N.A.
42.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
96.6
N.A.
N.A.
76.3
75.2
N.A.
N.A.
36.7
N.A.
56.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
N.A.
N.A.
13.3
20
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
26.6
26.6
N.A.
N.A.
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
34
0
0
34
0
0
17
17
0
0
0
0
% A
% Cys:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
17
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
34
17
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
17
0
34
0
0
0
0
0
% G
% His:
34
0
17
34
0
0
0
0
0
0
0
0
34
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
34
17
0
0
0
0
% I
% Lys:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
67
0
0
34
0
0
17
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
17
% M
% Asn:
0
0
34
17
0
0
0
0
0
0
0
34
0
0
0
% N
% Pro:
0
17
0
0
0
34
0
0
50
0
0
17
34
17
17
% P
% Gln:
0
0
0
17
0
0
0
0
17
0
0
0
0
67
0
% Q
% Arg:
0
0
34
0
17
0
0
17
0
0
0
0
17
17
0
% R
% Ser:
0
0
0
0
0
0
34
0
34
17
17
34
0
0
0
% S
% Thr:
0
0
0
0
34
0
0
34
0
0
17
0
0
0
0
% T
% Val:
34
17
0
0
0
0
34
0
0
0
0
0
17
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _