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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA5
All Species:
36.97
Human Site:
T274
Identified Species:
58.1
UniProt:
P11021
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11021
NP_005338.1
654
72333
T274
I
K
L
Y
K
K
K
T
G
K
D
V
R
K
D
Chimpanzee
Pan troglodytes
XP_001144115
615
68321
Y270
M
E
H
F
I
K
L
Y
K
K
K
T
G
K
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537847
666
73644
T274
I
K
L
Y
K
K
K
T
G
K
D
V
R
K
D
Cat
Felis silvestris
Mouse
Mus musculus
P20029
655
72404
T275
I
K
L
Y
K
K
K
T
G
K
D
V
R
K
D
Rat
Rattus norvegicus
P06761
654
72328
T274
I
K
L
Y
K
K
K
T
G
K
D
V
R
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90593
652
72000
T272
I
K
L
Y
K
K
K
T
G
K
D
V
R
K
D
Frog
Xenopus laevis
Q91883
658
72617
T275
I
K
L
Y
K
K
K
T
G
K
D
V
R
A
D
Zebra Danio
Brachydanio rerio
NP_998223
650
71956
T272
I
K
L
Y
K
K
K
T
G
K
D
V
R
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29844
656
72242
K274
I
K
L
Y
K
K
K
K
G
K
D
I
R
K
D
Honey Bee
Apis mellifera
NP_001153524
658
72847
K276
T
K
L
Y
K
K
K
K
G
K
D
I
R
K
D
Nematode Worm
Caenorhab. elegans
P27420
661
73005
S279
I
K
L
Y
K
K
K
S
G
K
D
L
R
K
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O24581
663
73138
Y278
I
K
L
I
K
K
K
Y
S
K
D
I
S
K
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKR3
669
73611
H280
I
K
L
I
K
K
K
H
Q
K
D
I
S
K
D
Baker's Yeast
Sacchar. cerevisiae
P16474
682
74449
H294
I
K
A
F
K
K
K
H
G
I
D
V
S
D
N
Red Bread Mold
Neurospora crassa
P78695
661
72313
H283
A
K
L
F
N
K
K
H
G
V
D
V
T
K
D
Conservation
Percent
Protein Identity:
100
94
N.A.
97.4
N.A.
98.4
98.4
N.A.
N.A.
96.4
92.7
91.7
N.A.
80.6
80.8
77.4
N.A.
Protein Similarity:
100
94
N.A.
98
N.A.
99
99
N.A.
N.A.
98.6
96.1
96
N.A.
90.6
90.1
88.8
N.A.
P-Site Identity:
100
26.6
N.A.
100
N.A.
100
100
N.A.
N.A.
100
93.3
100
N.A.
86.6
80
86.6
N.A.
P-Site Similarity:
100
46.6
N.A.
100
N.A.
100
100
N.A.
N.A.
100
93.3
100
N.A.
93.3
86.6
100
N.A.
Percent
Protein Identity:
N.A.
67.8
N.A.
67.1
64.6
67
Protein Similarity:
N.A.
82.8
N.A.
80.5
77.8
81
P-Site Identity:
N.A.
66.6
N.A.
66.6
53.3
60
P-Site Similarity:
N.A.
73.3
N.A.
73.3
66.6
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
94
0
0
7
94
% D
% Glu:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
80
0
0
0
7
0
0
% G
% His:
0
0
7
0
0
0
0
20
0
0
0
0
0
0
0
% H
% Ile:
80
0
0
14
7
0
0
0
0
7
0
27
0
0
0
% I
% Lys:
0
94
0
0
87
100
94
14
7
87
7
0
0
87
0
% K
% Leu:
0
0
87
0
0
0
7
0
0
0
0
7
0
0
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
0
% R
% Ser:
0
0
0
0
0
0
0
7
7
0
0
0
20
0
0
% S
% Thr:
7
0
0
0
0
0
0
47
0
0
0
7
7
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
7
0
60
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
67
0
0
0
14
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _