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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA5
All Species:
44.24
Human Site:
Y635
Identified Species:
69.52
UniProt:
P11021
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11021
NP_005338.1
654
72333
Y635
Q
P
I
I
S
K
L
Y
G
S
A
G
P
P
P
Chimpanzee
Pan troglodytes
XP_001144115
615
68321
Y596
Q
P
I
I
S
K
L
Y
G
S
A
G
P
P
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537847
666
73644
Y647
Q
P
I
I
S
K
L
Y
G
S
A
G
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P20029
655
72404
Y636
Q
P
I
I
S
K
L
Y
G
S
G
G
P
P
P
Rat
Rattus norvegicus
P06761
654
72328
Y635
Q
P
I
I
S
K
L
Y
G
S
G
G
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90593
652
72000
Y633
Q
P
I
V
S
K
L
Y
G
S
A
G
P
P
P
Frog
Xenopus laevis
Q91883
658
72617
Y636
Q
P
I
V
G
K
L
Y
G
G
A
G
A
P
P
Zebra Danio
Brachydanio rerio
NP_998223
650
71956
S630
E
V
V
Q
P
I
V
S
K
L
Y
G
S
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29844
656
72242
Y635
Q
P
V
I
A
K
L
Y
Q
G
A
G
G
A
P
Honey Bee
Apis mellifera
NP_001153524
658
72847
Y637
Q
P
I
I
A
K
L
Y
Q
G
A
G
G
G
V
Nematode Worm
Caenorhab. elegans
P27420
661
73005
Y640
Q
P
I
V
S
K
L
Y
K
D
A
G
A
G
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O24581
663
73138
Y641
N
P
I
V
S
A
V
Y
Q
R
S
G
G
A
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKR3
669
73611
Y643
N
P
I
I
T
A
V
Y
Q
R
S
G
G
A
P
Baker's Yeast
Sacchar. cerevisiae
P16474
682
74449
Y654
Y
P
I
T
S
K
L
Y
G
G
A
D
G
S
G
Red Bread Mold
Neurospora crassa
P78695
661
72313
S642
N
V
A
Y
P
I
T
S
K
L
Y
S
Q
G
G
Conservation
Percent
Protein Identity:
100
94
N.A.
97.4
N.A.
98.4
98.4
N.A.
N.A.
96.4
92.7
91.7
N.A.
80.6
80.8
77.4
N.A.
Protein Similarity:
100
94
N.A.
98
N.A.
99
99
N.A.
N.A.
98.6
96.1
96
N.A.
90.6
90.1
88.8
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
73.3
6.6
N.A.
60
60
60
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
100
80
26.6
N.A.
73.3
66.6
66.6
N.A.
Percent
Protein Identity:
N.A.
67.8
N.A.
67.1
64.6
67
Protein Similarity:
N.A.
82.8
N.A.
80.5
77.8
81
P-Site Identity:
N.A.
40
N.A.
40
53.3
0
P-Site Similarity:
N.A.
60
N.A.
60
53.3
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
14
14
0
0
0
0
60
0
14
27
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% D
% Glu:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
7
0
0
0
54
27
14
87
34
20
27
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
80
54
0
14
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
74
0
0
20
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
74
0
0
14
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
87
0
0
14
0
0
0
0
0
0
0
40
47
67
% P
% Gln:
67
0
0
7
0
0
0
0
27
0
0
0
7
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
0
% R
% Ser:
0
0
0
0
60
0
0
14
0
40
14
7
7
7
0
% S
% Thr:
0
0
0
7
7
0
7
0
0
0
0
0
0
0
0
% T
% Val:
0
14
14
27
0
0
20
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
0
0
87
0
0
14
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _