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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LAMC1 All Species: 27.58
Human Site: T252 Identified Species: 67.41
UniProt: P11047 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11047 NP_002284.3 1609 177603 T252 T A T D I R V T L N R L N T F
Chimpanzee Pan troglodytes XP_001162648 1609 177614 T252 T A T D I R V T L N R L N T F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537156 1496 165723 S222 W R R A T A E S A S E C L P C
Cat Felis silvestris
Mouse Mus musculus P02468 1607 177280 T250 T A T D I R V T L N R L N T F
Rat Rattus norvegicus Q924Z9 604 67820
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516008 1722 189393 T365 T A T D I R V T L N R L N T F
Chicken Gallus gallus Q90922 606 68108
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LVF0 1593 176187 T236 T A T D I R V T L N R L N T F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P15215 1639 182321 T265 T A T D I R I T L D R L N T F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18823 1535 170219 S238 T A S A I R I S L N R M N T F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 N.A. 88 N.A. 92.5 20.7 N.A. 82.9 20.9 N.A. 68.6 N.A. 40.5 N.A. 39.2 N.A.
Protein Similarity: 100 99.5 N.A. 91.3 N.A. 96.4 27.3 N.A. 88.9 27.4 N.A. 81.9 N.A. 59.1 N.A. 57.1 N.A.
P-Site Identity: 100 100 N.A. 0 N.A. 100 0 N.A. 100 0 N.A. 100 N.A. 86.6 N.A. 66.6 N.A.
P-Site Similarity: 100 100 N.A. 13.3 N.A. 100 0 N.A. 100 0 N.A. 100 N.A. 100 N.A. 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 70 0 20 0 10 0 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % C
% Asp: 0 0 0 60 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 70 0 20 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 70 0 0 60 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 60 0 0 70 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 10 0 0 70 0 0 0 0 70 0 0 0 0 % R
% Ser: 0 0 10 0 0 0 0 20 0 10 0 0 0 0 0 % S
% Thr: 70 0 60 0 10 0 0 60 0 0 0 0 0 70 0 % T
% Val: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _