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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNMT
All Species:
28.48
Human Site:
S193
Identified Species:
69.63
UniProt:
P11086
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11086
NP_002677.1
282
30855
S193
A
V
S
P
D
L
A
S
F
Q
R
A
L
D
H
Chimpanzee
Pan troglodytes
XP_511459
282
30765
S193
A
V
S
P
D
L
A
S
F
Q
R
A
L
D
H
Rhesus Macaque
Macaca mulatta
XP_001089850
282
30995
S193
A
V
S
P
D
L
A
S
F
Q
R
A
L
D
H
Dog
Lupus familis
XP_548143
291
31794
S201
A
V
S
P
D
L
P
S
F
Q
R
A
L
D
H
Cat
Felis silvestris
Mouse
Mus musculus
P40935
295
32526
S204
A
V
S
P
D
L
T
S
F
Q
R
A
L
H
H
Rat
Rattus norvegicus
P10937
285
31651
S194
A
V
S
P
D
L
P
S
F
R
Q
A
L
Y
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510530
373
40233
S283
A
V
S
P
D
K
A
S
F
Q
R
A
L
D
H
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083598
253
28304
A163
V
A
C
K
D
I
D
A
Y
K
D
A
V
R
N
Zebra Danio
Brachydanio rerio
XP_002666387
264
29340
S176
S
V
T
H
D
L
L
S
F
T
D
A
L
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34254
273
30841
A194
Y
S
C
E
T
L
E
A
Y
F
R
A
V
R
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
95.3
84.5
N.A.
81.6
82.8
N.A.
56
N.A.
39
43.9
N.A.
N.A.
N.A.
24.8
N.A.
Protein Similarity:
100
99.6
97.5
90.3
N.A.
87.4
89.8
N.A.
62.2
N.A.
54.6
60.2
N.A.
N.A.
N.A.
41.4
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
73.3
N.A.
93.3
N.A.
13.3
46.6
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
93.3
N.A.
53.3
66.6
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
10
0
0
0
0
40
20
0
0
0
100
0
0
0
% A
% Cys:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
90
0
10
0
0
0
20
0
0
50
0
% D
% Glu:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
80
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
70
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
10
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
80
10
0
0
0
0
0
80
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% N
% Pro:
0
0
0
70
0
0
20
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
60
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
70
0
0
30
0
% R
% Ser:
10
10
70
0
0
0
0
80
0
0
0
0
0
0
10
% S
% Thr:
0
0
10
0
10
0
10
0
0
10
0
0
0
0
0
% T
% Val:
10
80
0
0
0
0
0
0
0
0
0
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
20
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _