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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNMT All Species: 5.84
Human Site: S7 Identified Species: 14.29
UniProt: P11086 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11086 NP_002677.1 282 30855 S7 _ M S G A D R S P N A G A A P
Chimpanzee Pan troglodytes XP_511459 282 30765 S7 _ M S G A D Q S P A A G A A P
Rhesus Macaque Macaca mulatta XP_001089850 282 30995 I7 _ M S G A D R I P A A G A A P
Dog Lupus familis XP_548143 291 31794 D15 P A A G A A P D A A P D A A P
Cat Felis silvestris
Mouse Mus musculus P40935 295 32526 K18 T G S G S D P K H A A E M D P
Rat Rattus norvegicus P10937 285 31651 K8 M D R G S D P K H T A G M D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510530 373 40233 G93 G G P L D R P G G G T M S D G
Chicken Gallus gallus
Frog Xenopus laevis NP_001083598 253 28304 D7 _ M Y Q S M F D P K T Y L A S
Zebra Danio Brachydanio rerio XP_002666387 264 29340 S7 _ M A T C M D S C Y Q G F D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34254 273 30841 N7 _ M T G T T E N D N T G E D E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 95.3 84.5 N.A. 81.6 82.8 N.A. 56 N.A. 39 43.9 N.A. N.A. N.A. 24.8 N.A.
Protein Similarity: 100 99.6 97.5 90.3 N.A. 87.4 89.8 N.A. 62.2 N.A. 54.6 60.2 N.A. N.A. N.A. 41.4 N.A.
P-Site Identity: 100 85.7 85.7 33.3 N.A. 33.3 26.6 N.A. 0 N.A. 21.4 28.5 N.A. N.A. N.A. 28.5 N.A.
P-Site Similarity: 100 92.8 85.7 40 N.A. 40 33.3 N.A. 13.3 N.A. 28.5 35.7 N.A. N.A. N.A. 42.8 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 20 0 40 10 0 0 10 40 50 0 40 50 0 % A
% Cys: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 10 50 10 20 10 0 0 10 0 50 0 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 10 10 0 10 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % F
% Gly: 10 20 0 70 0 0 0 10 10 10 0 60 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 20 0 10 0 0 0 0 0 % K
% Leu: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % L
% Met: 10 60 0 0 0 20 0 0 0 0 0 10 20 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 20 0 0 0 0 0 % N
% Pro: 10 0 10 0 0 0 40 0 40 0 10 0 0 0 60 % P
% Gln: 0 0 0 10 0 0 10 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 10 0 0 10 20 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 40 0 30 0 0 30 0 0 0 0 10 0 20 % S
% Thr: 10 0 10 10 10 10 0 0 0 10 30 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 10 0 10 0 0 0 % Y
% Spaces: 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _