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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA8
All Species:
40
Human Site:
S121
Identified Species:
88
UniProt:
P11142
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11142
NP_006588.1
646
70898
S121
F
Y
P
E
E
V
S
S
M
V
L
T
K
M
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_859472
616
67720
E110
V
Q
V
E
Y
K
G
E
T
K
S
F
Y
P
E
Cat
Felis silvestris
Mouse
Mus musculus
P17156
633
69722
S122
F
F
P
E
E
I
S
S
M
V
L
T
K
M
K
Rat
Rattus norvegicus
P63018
646
70853
S121
F
Y
P
E
E
V
S
S
M
V
L
T
K
M
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510947
681
74598
S156
F
Y
P
E
E
V
S
S
M
V
L
T
K
M
K
Chicken
Gallus gallus
O73885
646
70808
S121
F
Y
P
E
E
I
S
S
M
V
L
T
K
M
K
Frog
Xenopus laevis
P02827
647
70897
S122
F
F
P
E
E
I
S
S
M
V
L
T
K
M
K
Zebra Danio
Brachydanio rerio
Q90473
649
70955
S121
F
Y
P
E
E
I
S
S
M
V
L
T
K
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11147
651
71113
S121
F
F
P
E
E
I
S
S
M
V
L
T
K
M
K
Honey Bee
Apis mellifera
NP_001153522
650
71067
S121
F
F
P
E
E
V
S
S
M
V
L
V
K
M
K
Nematode Worm
Caenorhab. elegans
P09446
640
69704
S122
F
T
P
E
E
I
S
S
M
V
L
L
K
M
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
95.3
N.A.
85.9
99.8
N.A.
94.4
97.9
84.6
93.5
N.A.
84.7
87
85.2
N.A.
Protein Similarity:
100
N.A.
N.A.
95.3
N.A.
92.7
100
N.A.
94.5
99
93.5
96.6
N.A.
91.8
93.5
91.3
N.A.
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
86.6
100
N.A.
100
93.3
86.6
93.3
N.A.
86.6
86.6
80
N.A.
P-Site Similarity:
100
N.A.
N.A.
13.3
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
93.3
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
100
91
0
0
10
0
0
0
0
0
0
10
% E
% Phe:
91
37
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
55
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
10
0
0
91
0
91
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
91
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
91
0
0
0
0
91
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
91
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
91
91
0
0
10
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
10
0
0
73
0
0
0
% T
% Val:
10
0
10
0
0
37
0
0
0
91
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
46
0
0
10
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _