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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPA8 All Species: 32.73
Human Site: Y611 Identified Species: 72
UniProt: P11142 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11142 NP_006588.1 646 70898 Y611 N P I I T K L Y Q S A G G M P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_859472 616 67720 Y581 N P I I T K L Y Q S A G G M P
Cat Felis silvestris
Mouse Mus musculus P17156 633 69722 K598 E K D E Y E H K Q K E L E R V
Rat Rattus norvegicus P63018 646 70853 Y611 N P I I T K L Y Q S A G G M P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510947 681 74598 Y646 N P I I T K L Y Q S A G G M P
Chicken Gallus gallus O73885 646 70808 Y611 N P I I T K L Y Q S A G G M P
Frog Xenopus laevis P02827 647 70897 Y612 Q P I I T K L Y Q G G V P G G
Zebra Danio Brachydanio rerio Q90473 649 70955 Y611 N P I I T K L Y Q S A G G M P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P11147 651 71113 Y611 N P I I T K L Y Q G A G F P P
Honey Bee Apis mellifera NP_001153522 650 71067 Y611 N P I V T K L Y Q G T G G M P
Nematode Worm Caenorhab. elegans P09446 640 69704 I608 E G L A N P I I S K L Y Q S A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 95.3 N.A. 85.9 99.8 N.A. 94.4 97.9 84.6 93.5 N.A. 84.7 87 85.2 N.A.
Protein Similarity: 100 N.A. N.A. 95.3 N.A. 92.7 100 N.A. 94.5 99 93.5 96.6 N.A. 91.8 93.5 91.3 N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. 6.6 100 N.A. 100 100 53.3 100 N.A. 80 80 0 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 13.3 100 N.A. 100 100 53.3 100 N.A. 80 86.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 64 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 19 0 0 10 0 10 0 0 0 0 10 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 28 10 73 64 10 10 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 82 73 0 0 10 10 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 82 0 10 0 19 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 0 82 0 0 0 10 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 64 0 % M
% Asn: 73 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 82 0 0 0 10 0 0 0 0 0 0 10 10 73 % P
% Gln: 10 0 0 0 0 0 0 0 91 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 0 0 0 0 0 0 0 10 55 0 0 0 10 0 % S
% Thr: 0 0 0 0 82 0 0 0 0 0 10 0 0 0 0 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 82 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _