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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UMPS All Species: 49.7
Human Site: S444 Identified Species: 72.89
UniProt: P11172 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11172 NP_000364.1 480 52222 S444 E V I G K R G S D I I I V G R
Chimpanzee Pan troglodytes XP_001169057 480 52278 S444 E V I G K R G S D I I I V G R
Rhesus Macaque Macaca mulatta XP_001113651 480 52065 S444 E V I G K R G S D I I I V G R
Dog Lupus familis XP_535769 569 61433 S533 E V I G K R G S D I I I V G R
Cat Felis silvestris
Mouse Mus musculus P13439 481 52274 S444 E V I G K R G S D V I I V G R
Rat Rattus norvegicus NP_001020573 481 52360 S444 E V V G K R G S D V I I V G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026431 479 51808 S441 E V I S E K G S D I I I V G R
Frog Xenopus laevis NP_001088036 473 51761 S432 E V I V N K G S D I I I V G R
Zebra Danio Brachydanio rerio NP_956468 479 51677 S441 D V I C T K G S D I I I V G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q01637 493 53401 A457 H V V K E R G A D I G V V G R
Honey Bee Apis mellifera XP_392009 468 52184 A432 E S V V N S G A D L A V V G R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785560 476 52060 S436 E V I T N R K S D I I I V G R
Poplar Tree Populus trichocarpa XP_002297746 475 51924 S440 S V I Y D R G S D I I I V G R
Maize Zea mays NP_001142238 476 51231 S441 S V I N Y R G S D I I I V G R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42586 476 51832 S440 S V I T E R G S D I I I V G R
Baker's Yeast Sacchar. cerevisiae P03962 267 29221 I232 S T G S D I I I V G R G L F A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 97.5 77.8 N.A. 88.5 89.8 N.A. N.A. 74.7 67.9 63.3 N.A. 46.6 45 N.A. 52
Protein Similarity: 100 98.7 98.9 81.7 N.A. 93.5 94.1 N.A. N.A. 86.8 80.6 80 N.A. 65.3 65.4 N.A. 70.6
P-Site Identity: 100 100 100 100 N.A. 93.3 86.6 N.A. N.A. 80 80 73.3 N.A. 53.3 40 N.A. 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 86.6 86.6 N.A. 80 66.6 N.A. 80
Percent
Protein Identity: 52.7 55.8 N.A. 54.5 29.1 N.A.
Protein Similarity: 70.2 72 N.A. 71.2 39.1 N.A.
P-Site Identity: 80 80 N.A. 80 0 N.A.
P-Site Similarity: 80 80 N.A. 86.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 13 0 0 7 0 0 0 7 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 13 0 0 0 94 0 0 0 0 0 0 % D
% Glu: 63 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 7 38 0 0 88 0 0 7 7 7 0 94 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 75 0 0 7 7 7 0 75 82 82 0 0 0 % I
% Lys: 0 0 0 7 38 19 7 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 7 0 0 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 19 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 69 0 0 0 0 7 0 0 0 94 % R
% Ser: 25 7 0 13 0 7 0 82 0 0 0 0 0 0 0 % S
% Thr: 0 7 0 13 7 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 88 19 13 0 0 0 0 7 13 0 13 94 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _