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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UMPS All Species: 38.18
Human Site: S45 Identified Species: 56
UniProt: P11172 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11172 NP_000364.1 480 52222 S45 I D L R G I V S R P R L L S Q
Chimpanzee Pan troglodytes XP_001169057 480 52278 S45 I D L R G I V S R P R L L S Q
Rhesus Macaque Macaca mulatta XP_001113651 480 52065 S45 I D L R G I V S R P R L L S Q
Dog Lupus familis XP_535769 569 61433 S134 I D L R G I V S R P R L L S Q
Cat Felis silvestris
Mouse Mus musculus P13439 481 52274 S45 I D L R G I V S R P R L L S Q
Rat Rattus norvegicus NP_001020573 481 52360 S45 I D L R G I V S R P R L L S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026431 479 51808 S43 V D L R G L A S R P S L L R L
Frog Xenopus laevis NP_001088036 473 51761 S41 F D L R M I V S H P S L L N Q
Zebra Danio Brachydanio rerio NP_956468 479 51677 S43 F D L R V I V S H P A L M N Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q01637 493 53401 S46 F D L R V I V S Y P D V M Q T
Honey Bee Apis mellifera XP_392009 468 52184 I41 Y F D L R V L I S H P K I M V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785560 476 52060 S40 F D L R V M V S Y P D I M D A
Poplar Tree Populus trichocarpa XP_002297746 475 51924 I40 Y I D L R L I I S Y P S L L R
Maize Zea mays NP_001142238 476 51231 L41 I Y L D L R A L V S H P R L L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42586 476 51832 V40 Y I D L R L I V S Y P S L L T
Baker's Yeast Sacchar. cerevisiae P03962 267 29221
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 97.5 77.8 N.A. 88.5 89.8 N.A. N.A. 74.7 67.9 63.3 N.A. 46.6 45 N.A. 52
Protein Similarity: 100 98.7 98.9 81.7 N.A. 93.5 94.1 N.A. N.A. 86.8 80.6 80 N.A. 65.3 65.4 N.A. 70.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 60 66.6 60 N.A. 46.6 0 N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 73.3 73.3 73.3 N.A. 60 20 N.A. 60
Percent
Protein Identity: 52.7 55.8 N.A. 54.5 29.1 N.A.
Protein Similarity: 70.2 72 N.A. 71.2 39.1 N.A.
P-Site Identity: 6.6 13.3 N.A. 6.6 0 N.A.
P-Site Similarity: 26.6 13.3 N.A. 20 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 13 0 0 0 7 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 69 19 7 0 0 0 0 0 0 13 0 0 7 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 25 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 44 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 13 7 7 0 0 0 0 % H
% Ile: 44 13 0 0 0 57 13 13 0 0 0 7 7 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % K
% Leu: 0 0 75 19 7 19 7 7 0 0 0 57 63 19 13 % L
% Met: 0 0 0 0 7 7 0 0 0 0 0 0 19 7 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 69 19 7 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 50 % Q
% Arg: 0 0 0 69 19 7 0 0 44 0 38 0 7 7 7 % R
% Ser: 0 0 0 0 0 0 0 69 19 7 13 13 0 38 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % T
% Val: 7 0 0 0 19 7 63 7 7 0 0 7 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 19 7 0 0 0 0 0 0 13 13 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _