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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UMPS All Species: 18.48
Human Site: T193 Identified Species: 27.11
UniProt: P11172 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11172 NP_000364.1 480 52222 T193 Q K K V D A E T V G R V K R F
Chimpanzee Pan troglodytes XP_001169057 480 52278 T193 Q K K I D A E T V G R V K R F
Rhesus Macaque Macaca mulatta XP_001113651 480 52065 T193 Q K K I D A E T V G R V K R F
Dog Lupus familis XP_535769 569 61433 M282 Q K K I D A E M V E R V K R F
Cat Felis silvestris
Mouse Mus musculus P13439 481 52274 M193 Q E K I D A D M V G R V K R F
Rat Rattus norvegicus NP_001020573 481 52360 M193 Q K K I D A E M V G R V K R F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026431 479 51808 M191 Q G E V D V E M V E K V K N F
Frog Xenopus laevis NP_001088036 473 51761 G186 L R S V G A V G S E T V S N V
Zebra Danio Brachydanio rerio NP_956468 479 51677 T191 A G R I D T D T A Q S V K R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q01637 493 53401 T194 A G R I E K S T V E A V A K Y
Honey Bee Apis mellifera XP_392009 468 52184 T186 L L E A N K I T P K I V K N V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785560 476 52060 V188 H G K I S A E V V Q S V K L F
Poplar Tree Populus trichocarpa XP_002297746 475 51924 T188 K G K L E E E T E K G V L R F
Maize Zea mays NP_001142238 476 51231 K189 H G K V T E E K A Q E V R Q F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42586 476 51832 V188 K G K I E V E V E V N L L K F
Baker's Yeast Sacchar. cerevisiae P03962 267 29221
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 97.5 77.8 N.A. 88.5 89.8 N.A. N.A. 74.7 67.9 63.3 N.A. 46.6 45 N.A. 52
Protein Similarity: 100 98.7 98.9 81.7 N.A. 93.5 94.1 N.A. N.A. 86.8 80.6 80 N.A. 65.3 65.4 N.A. 70.6
P-Site Identity: 100 93.3 93.3 80 N.A. 73.3 86.6 N.A. N.A. 53.3 20 40 N.A. 20 20 N.A. 46.6
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. N.A. 66.6 26.6 60 N.A. 53.3 33.3 N.A. 53.3
Percent
Protein Identity: 52.7 55.8 N.A. 54.5 29.1 N.A.
Protein Similarity: 70.2 72 N.A. 71.2 39.1 N.A.
P-Site Identity: 40 33.3 N.A. 20 0 N.A.
P-Site Similarity: 60 46.6 N.A. 53.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 7 0 50 0 0 13 0 7 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 50 0 13 0 0 0 0 0 0 0 0 % D
% Glu: 0 7 13 0 19 13 63 0 13 25 7 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75 % F
% Gly: 0 44 0 0 7 0 0 7 0 32 7 0 0 0 0 % G
% His: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 57 0 0 7 0 0 0 7 0 0 0 0 % I
% Lys: 13 32 63 0 0 13 0 7 0 13 7 0 63 13 0 % K
% Leu: 13 7 0 7 0 0 0 0 0 0 0 7 13 7 0 % L
% Met: 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 0 7 0 0 19 0 % N
% Pro: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % P
% Gln: 44 0 0 0 0 0 0 0 0 19 0 0 0 7 0 % Q
% Arg: 0 7 13 0 0 0 0 0 0 0 38 0 7 50 0 % R
% Ser: 0 0 7 0 7 0 7 0 7 0 13 0 7 0 0 % S
% Thr: 0 0 0 0 7 7 0 44 0 0 7 0 0 0 0 % T
% Val: 0 0 0 25 0 13 7 13 57 7 0 88 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _