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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UMPS
All Species:
40.43
Human Site:
Y474
Identified Species:
59.3
UniProt:
P11172
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11172
NP_000364.1
480
52222
Y474
R
K
A
A
W
E
A
Y
L
S
R
L
G
V
_
Chimpanzee
Pan troglodytes
XP_001169057
480
52278
Y474
R
K
A
A
W
E
A
Y
L
S
R
L
G
V
_
Rhesus Macaque
Macaca mulatta
XP_001113651
480
52065
Y474
R
K
A
A
W
E
A
Y
L
S
R
L
G
V
_
Dog
Lupus familis
XP_535769
569
61433
Y563
R
K
A
A
W
E
A
Y
L
S
R
L
G
I
_
Cat
Felis silvestris
Mouse
Mus musculus
P13439
481
52274
Y474
R
K
A
A
W
E
A
Y
L
S
R
L
A
V
Q
Rat
Rattus norvegicus
NP_001020573
481
52360
Y474
R
K
A
A
W
E
A
Y
L
S
R
L
A
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026431
479
51808
Y471
R
K
A
A
W
E
S
Y
I
S
R
L
G
V
H
Frog
Xenopus laevis
NP_001088036
473
51761
Y462
R
K
A
G
W
E
A
Y
L
T
A
M
G
N
V
Zebra Danio
Brachydanio rerio
NP_956468
479
51677
Y471
R
T
A
G
W
E
A
Y
L
K
R
L
S
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01637
493
53401
Y487
R
D
R
L
W
A
A
Y
Q
D
R
V
A
K
_
Honey Bee
Apis mellifera
XP_392009
468
52184
Y462
K
K
E
L
W
T
A
Y
L
K
R
I
S
N
_
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785560
476
52060
Y466
Q
A
A
G
M
K
A
Y
H
Q
L
L
E
G
E
Poplar Tree
Populus trichocarpa
XP_002297746
475
51924
Maize
Zea mays
NP_001142238
476
51231
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42586
476
51832
Y470
R
V
Q
G
W
N
A
Y
L
E
K
C
S
Q
_
Baker's Yeast
Sacchar. cerevisiae
P03962
267
29221
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
97.5
77.8
N.A.
88.5
89.8
N.A.
N.A.
74.7
67.9
63.3
N.A.
46.6
45
N.A.
52
Protein Similarity:
100
98.7
98.9
81.7
N.A.
93.5
94.1
N.A.
N.A.
86.8
80.6
80
N.A.
65.3
65.4
N.A.
70.6
P-Site Identity:
100
100
100
92.8
N.A.
86.6
86.6
N.A.
N.A.
80
60
60
N.A.
35.7
42.8
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
93.3
73.3
66.6
N.A.
42.8
57.1
N.A.
40
Percent
Protein Identity:
52.7
55.8
N.A.
54.5
29.1
N.A.
Protein Similarity:
70.2
72
N.A.
71.2
39.1
N.A.
P-Site Identity:
0
0
N.A.
35.7
0
N.A.
P-Site Similarity:
0
0
N.A.
42.8
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
63
44
0
7
75
0
0
0
7
0
19
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% D
% Glu:
0
0
7
0
0
57
0
0
0
7
0
0
7
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
25
0
0
0
0
0
0
0
0
38
7
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
7
0
7
0
% I
% Lys:
7
57
0
0
0
7
0
0
0
13
7
0
0
7
0
% K
% Leu:
0
0
0
13
0
0
0
0
63
0
7
57
0
7
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
0
0
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
7
0
0
0
0
0
7
7
0
0
0
7
13
% Q
% Arg:
69
0
7
0
0
0
0
0
0
0
63
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
7
0
0
44
0
0
19
0
0
% S
% Thr:
0
7
0
0
0
7
0
0
0
7
0
0
0
0
0
% T
% Val:
0
7
0
0
0
0
0
0
0
0
0
7
0
38
7
% V
% Trp:
0
0
0
0
75
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
44
% _