KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDHB
All Species:
23.94
Human Site:
S16
Identified Species:
40.51
UniProt:
P11177
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11177
NP_000916.2
359
39233
S16
R
R
P
L
R
E
V
S
G
L
L
K
R
R
F
Chimpanzee
Pan troglodytes
XP_526215
341
37181
T16
R
R
P
L
R
E
V
T
V
R
D
A
I
N
Q
Rhesus Macaque
Macaca mulatta
XP_001096445
359
39245
S16
R
R
P
L
R
E
V
S
G
L
L
K
R
R
F
Dog
Lupus familis
XP_533778
359
39231
S16
R
R
P
L
E
Q
V
S
G
L
L
R
R
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D051
359
38919
S16
R
G
P
L
R
Q
A
S
G
L
L
K
R
R
F
Rat
Rattus norvegicus
P49432
359
38964
S16
R
G
P
L
R
Q
A
S
G
L
L
K
R
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414404
359
38858
L16
L
L
V
P
R
G
R
L
L
P
P
R
R
G
L
Frog
Xenopus laevis
NP_001084345
360
39106
S16
C
G
G
K
S
S
V
S
L
L
L
Q
R
S
F
Zebra Danio
Brachydanio rerio
NP_998319
359
39290
S16
R
S
G
K
S
A
V
S
A
V
L
R
R
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651668
365
39333
A16
A
A
S
S
A
Q
R
A
F
S
T
S
Q
K
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O44451
352
38122
G16
L
F
V
A
R
L
A
G
T
S
T
R
A
A
S
Sea Urchin
Strong. purpuratus
XP_785251
1079
120383
G16
F
A
Q
K
I
L
P
G
A
F
V
R
R
C
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38799
363
39157
T19
G
A
S
T
L
R
R
T
R
F
A
L
V
S
A
Baker's Yeast
Sacchar. cerevisiae
P32473
366
40035
V22
R
R
A
P
T
S
F
V
R
P
S
A
A
A
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
99.7
96.3
N.A.
93.5
94.4
N.A.
N.A.
83.8
83.3
83.8
N.A.
64.6
N.A.
64.6
22.9
Protein Similarity:
100
94.9
99.7
98.8
N.A.
97.4
97.7
N.A.
N.A.
92.4
92.2
92.1
N.A.
76.9
N.A.
79.3
28.5
P-Site Identity:
100
46.6
100
80
N.A.
80
80
N.A.
N.A.
13.3
40
40
N.A.
0
N.A.
6.6
6.6
P-Site Similarity:
100
53.3
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
20
46.6
53.3
N.A.
26.6
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
57.3
57.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
74.6
75.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
22
8
8
8
8
22
8
15
0
8
15
15
15
22
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
8
22
0
0
0
0
0
0
0
8
0
% E
% Phe:
8
8
0
0
0
0
8
0
8
15
0
0
0
0
50
% F
% Gly:
8
22
15
0
0
8
0
15
36
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
22
0
0
0
0
0
0
0
29
0
8
0
% K
% Leu:
15
8
0
43
8
15
0
8
15
43
50
8
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
43
15
0
0
8
0
0
15
8
0
0
0
0
% P
% Gln:
0
0
8
0
0
29
0
0
0
0
0
8
8
0
8
% Q
% Arg:
58
36
0
0
50
8
22
0
15
8
0
36
65
36
0
% R
% Ser:
0
8
15
8
15
15
0
50
0
15
8
8
0
15
8
% S
% Thr:
0
0
0
8
8
0
0
15
8
0
15
0
0
0
0
% T
% Val:
0
0
15
0
0
0
43
8
8
8
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _