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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDHB
All Species:
33.03
Human Site:
T26
Identified Species:
55.9
UniProt:
P11177
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11177
NP_000916.2
359
39233
T26
L
K
R
R
F
H
W
T
A
P
A
A
L
Q
V
Chimpanzee
Pan troglodytes
XP_526215
341
37181
D26
D
A
I
N
Q
G
M
D
E
E
L
E
R
D
E
Rhesus Macaque
Macaca mulatta
XP_001096445
359
39245
T26
L
K
R
R
F
H
W
T
A
P
T
A
L
Q
V
Dog
Lupus familis
XP_533778
359
39231
T26
L
R
R
R
F
H
R
T
A
P
A
A
L
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D051
359
38919
S26
L
K
R
R
F
H
R
S
A
P
A
A
V
Q
L
Rat
Rattus norvegicus
P49432
359
38964
S26
L
K
R
R
F
H
R
S
A
P
A
A
V
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414404
359
38858
S26
P
R
R
G
L
R
L
S
A
P
A
A
I
Q
V
Frog
Xenopus laevis
NP_001084345
360
39106
S26
L
Q
R
S
F
H
R
S
S
P
A
A
L
Q
V
Zebra Danio
Brachydanio rerio
NP_998319
359
39290
T26
L
R
R
E
F
H
R
T
P
P
A
A
V
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651668
365
39333
A26
T
S
Q
K
A
L
A
A
K
Q
M
T
V
R
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O44451
352
38122
T26
T
R
A
A
S
T
M
T
V
R
D
A
L
N
Q
Sea Urchin
Strong. purpuratus
XP_785251
1079
120383
S26
V
R
R
C
L
S
T
S
S
P
A
S
G
Q
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38799
363
39157
Y29
A
L
V
S
A
R
S
Y
A
A
G
A
K
E
M
Baker's Yeast
Sacchar. cerevisiae
P32473
366
40035
R32
S
A
A
A
A
A
L
R
F
S
S
T
K
T
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
99.7
96.3
N.A.
93.5
94.4
N.A.
N.A.
83.8
83.3
83.8
N.A.
64.6
N.A.
64.6
22.9
Protein Similarity:
100
94.9
99.7
98.8
N.A.
97.4
97.7
N.A.
N.A.
92.4
92.2
92.1
N.A.
76.9
N.A.
79.3
28.5
P-Site Identity:
100
0
93.3
86.6
N.A.
73.3
73.3
N.A.
N.A.
46.6
66.6
66.6
N.A.
0
N.A.
20
26.6
P-Site Similarity:
100
0
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
66.6
86.6
80
N.A.
26.6
N.A.
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
57.3
57.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
74.6
75.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
15
15
22
8
8
8
50
8
58
72
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
8
0
0
8
0
0
8
8
% D
% Glu:
0
0
0
8
0
0
0
0
8
8
0
8
0
8
8
% E
% Phe:
0
0
0
0
50
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
8
0
0
0
0
8
0
8
0
0
% G
% His:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
29
0
8
0
0
0
0
8
0
0
0
15
0
0
% K
% Leu:
50
8
0
0
15
8
15
0
0
0
8
0
36
0
15
% L
% Met:
0
0
0
0
0
0
15
0
0
0
8
0
0
0
22
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
8
0
0
0
0
0
0
0
8
65
0
0
0
0
0
% P
% Gln:
0
8
8
0
8
0
0
0
0
8
0
0
0
65
8
% Q
% Arg:
0
36
65
36
0
15
36
8
0
8
0
0
8
8
0
% R
% Ser:
8
8
0
15
8
8
8
36
15
8
8
8
0
0
0
% S
% Thr:
15
0
0
0
0
8
8
36
0
0
8
15
0
8
0
% T
% Val:
8
0
8
0
0
0
0
0
8
0
0
0
29
0
43
% V
% Trp:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _