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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DBT
All Species:
39.09
Human Site:
S469
Identified Species:
66.15
UniProt:
P11182
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11182
NP_001909.2
482
53487
S469
R
F
S
N
L
W
K
S
Y
L
E
N
P
A
F
Chimpanzee
Pan troglodytes
NP_001136231
524
58122
S511
R
F
S
N
L
W
K
S
Y
L
E
N
P
A
F
Rhesus Macaque
Macaca mulatta
XP_001107312
482
53448
S469
R
F
S
N
L
W
K
S
Y
L
E
N
P
A
F
Dog
Lupus familis
XP_537055
482
53272
S469
R
F
S
N
L
W
K
S
Y
L
E
N
P
A
F
Cat
Felis silvestris
Mouse
Mus musculus
P53395
482
53142
S469
R
F
S
N
L
W
K
S
Y
L
E
N
P
A
F
Rat
Rattus norvegicus
NP_445764
482
53255
S469
R
F
S
N
L
W
K
S
Y
L
E
N
P
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515929
309
33592
P301
W
K
S
Y
L
E
N
P
A
S
M
L
L
D
L
Chicken
Gallus gallus
NP_989987
493
53980
S480
R
F
S
N
L
W
K
S
Y
L
E
N
P
A
L
Frog
Xenopus laevis
NP_001087792
492
53684
S479
R
F
S
N
L
W
K
S
Y
L
E
N
P
S
L
Zebra Danio
Brachydanio rerio
NP_001013533
493
53907
S480
R
F
S
N
L
W
R
S
Y
L
E
N
P
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573000
462
50055
E454
N
V
W
K
Q
Y
L
E
N
P
A
L
F
L
L
Honey Bee
Apis mellifera
XP_624936
501
57231
Y489
K
Y
S
N
F
W
K
Y
Y
I
E
N
P
I
F
Nematode Worm
Caenorhab. elegans
NP_495670
448
49673
P440
W
K
F
Y
L
E
H
P
S
A
M
L
A
Q
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5M729
539
58449
G529
E
W
L
K
A
F
K
G
Y
I
E
N
P
K
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
98.1
91.4
N.A.
87.7
87.7
N.A.
52.7
75.4
73.5
69.7
N.A.
49.1
47.9
50.8
N.A.
Protein Similarity:
100
91.9
99.1
96.2
N.A.
93.3
93.9
N.A.
59.3
86
85.5
80.1
N.A.
66.1
63.6
66.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
93.3
86.6
86.6
N.A.
0
60
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
93.3
93.3
93.3
N.A.
6.6
80
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
8
8
0
8
58
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
8
0
0
0
0
15
0
8
0
0
79
0
0
0
0
% E
% Phe:
0
65
8
0
8
8
0
0
0
0
0
0
8
0
50
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
15
0
0
0
8
0
% I
% Lys:
8
15
0
15
0
0
72
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
8
0
79
0
8
0
0
65
0
22
8
8
36
% L
% Met:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% M
% Asn:
8
0
0
72
0
0
8
0
8
0
0
79
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
15
0
8
0
0
79
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
65
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
79
0
0
0
0
65
8
8
0
0
0
8
15
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
15
8
8
0
0
72
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
15
0
8
0
8
79
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _