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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PYGM All Species: 34.85
Human Site: Y549 Identified Species: 69.7
UniProt: P11217 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11217 NP_005600.1 842 97092 Y549 N K L K F A A Y L E R E Y K V
Chimpanzee Pan troglodytes XP_001165783 842 97084 Y549 N K L K F A A Y L E R E Y K V
Rhesus Macaque Macaca mulatta XP_001114805 842 97148 Y549 N K L K F A A Y L E R E Y K V
Dog Lupus familis XP_853123 842 97190 Y549 N K L K F A A Y L E R E Y K V
Cat Felis silvestris
Mouse Mus musculus Q9WUB3 842 97268 Y549 N K L K F S A Y L E R E Y K V
Rat Rattus norvegicus P09812 842 97255 Y549 N K L K F S A Y L E T E Y K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026205 843 96712 Y549 N K L K F S A Y L E E R Y K V
Frog Xenopus laevis NP_001085064 843 97075 Y549 N K L K F A A Y L E Q E Y K V
Zebra Danio Brachydanio rerio NP_001018464 842 96914 H549 N K L K F A V H L E E H Y K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9XTL9 844 96978 I549 N K L K L A A I L E K D Y G V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SD76 841 95141 Y552 N K K R L A Q Y I E R V T G V
Baker's Yeast Sacchar. cerevisiae P06738 902 103525 Y619 V D I I N R E Y L D D T L F D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.6 97.5 N.A. 97 95.2 N.A. N.A. 82.9 83.1 84.8 N.A. 73.2 N.A. N.A. N.A.
Protein Similarity: 100 99.6 99.7 99.2 N.A. 99.2 98.4 N.A. N.A. 92.8 93.7 93.1 N.A. 86 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 86.6 N.A. N.A. 80 93.3 73.3 N.A. 66.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 86.6 100 80 N.A. 80 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 46.4 47.3 N.A.
Protein Similarity: N.A. N.A. N.A. 62.8 65.4 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 67 75 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 9 9 9 0 0 9 % D
% Glu: 0 0 0 0 0 0 9 0 0 92 17 59 0 0 0 % E
% Phe: 0 0 0 0 75 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 0 % H
% Ile: 0 0 9 9 0 0 0 9 9 0 0 0 0 0 0 % I
% Lys: 0 92 9 84 0 0 0 0 0 0 9 0 0 75 0 % K
% Leu: 0 0 84 0 17 0 0 0 92 0 0 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 92 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % Q
% Arg: 0 0 0 9 0 9 0 0 0 0 50 9 0 0 0 % R
% Ser: 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 9 9 9 0 0 % T
% Val: 9 0 0 0 0 0 9 0 0 0 0 9 0 0 92 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 84 0 0 0 0 84 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _