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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRM1
All Species:
26.67
Human Site:
S291
Identified Species:
58.67
UniProt:
P11229
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11229
NP_000729.2
460
51421
S291
S
M
E
S
L
T
S
S
E
G
E
E
P
G
S
Chimpanzee
Pan troglodytes
Q9N2A4
590
65944
S352
S
L
E
N
S
A
S
S
D
E
E
D
I
G
S
Rhesus Macaque
Macaca mulatta
P56489
460
51414
S291
S
M
E
S
L
T
S
S
E
G
E
E
P
G
S
Dog
Lupus familis
XP_540897
460
51520
S291
S
M
E
S
L
T
S
S
E
G
E
E
P
G
S
Cat
Felis silvestris
Mouse
Mus musculus
P12657
460
51310
S291
S
M
E
S
L
T
S
S
E
G
E
E
P
G
S
Rat
Rattus norvegicus
P08482
460
51350
S291
S
M
E
S
L
T
S
S
E
G
E
E
P
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49578
639
71958
S400
S
L
E
N
S
A
S
S
D
E
E
D
I
T
A
Frog
Xenopus laevis
P30544
484
54107
S300
S
N
E
S
S
S
A
S
L
S
H
N
P
P
E
Zebra Danio
Brachydanio rerio
XP_700381
665
73838
R404
S
D
K
S
G
P
N
R
E
A
D
Q
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16395
805
86605
E434
Y
A
T
P
V
T
I
E
T
P
L
Q
S
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U7D5
611
69544
A417
A
S
M
R
N
G
S
A
R
F
R
S
R
P
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.6
99.5
98
N.A.
98
98.6
N.A.
N.A.
44.1
46
44.6
N.A.
31.5
N.A.
34.7
N.A.
Protein Similarity:
100
60.5
99.7
98.9
N.A.
98.6
99.3
N.A.
N.A.
55.7
61.9
53.8
N.A.
41.7
N.A.
46.9
N.A.
P-Site Identity:
100
46.6
100
100
N.A.
100
100
N.A.
N.A.
33.3
33.3
26.6
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
73.3
100
100
N.A.
100
100
N.A.
N.A.
66.6
46.6
53.3
N.A.
20
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
19
10
10
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
19
0
10
19
0
0
0
% D
% Glu:
0
0
73
0
0
0
0
10
55
19
64
46
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
0
0
0
46
0
0
0
55
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
19
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
19
0
0
46
0
0
0
10
0
10
0
0
0
0
% L
% Met:
0
46
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
19
10
0
10
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
10
0
10
0
0
0
10
0
0
55
19
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
10
10
0
10
0
10
0
0
% R
% Ser:
82
10
0
64
28
10
73
73
0
10
0
10
19
19
73
% S
% Thr:
0
0
10
0
0
55
0
0
10
0
0
0
0
10
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _