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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHRM1 All Species: 43.94
Human Site: T128 Identified Species: 96.67
UniProt: P11229 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11229 NP_000729.2 460 51421 T128 F D R Y F S V T R P L S Y R A
Chimpanzee Pan troglodytes Q9N2A4 590 65944 T171 F D R Y F S I T R P L T Y R A
Rhesus Macaque Macaca mulatta P56489 460 51414 T128 F D R Y F S V T R P L S Y R A
Dog Lupus familis XP_540897 460 51520 T128 F D R Y F S V T R P L S Y R A
Cat Felis silvestris
Mouse Mus musculus P12657 460 51310 T128 F D R Y F S V T R P L S Y R A
Rat Rattus norvegicus P08482 460 51350 T128 F D R Y F S V T R P L S Y R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P49578 639 71958 T219 F D R Y F S I T R P L T Y R A
Frog Xenopus laevis P30544 484 54107 T136 L E R X F C V T K P L T Y P A
Zebra Danio Brachydanio rerio XP_700381 665 73838 T241 F D R Y F S I T R P L T Y R A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16395 805 86605 T207 F D R Y F S V T R P L T Y R A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U7D5 611 69544 T168 F D R Y F S V T R P L S Y R P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 48.6 99.5 98 N.A. 98 98.6 N.A. N.A. 44.1 46 44.6 N.A. 31.5 N.A. 34.7 N.A.
Protein Similarity: 100 60.5 99.7 98.9 N.A. 98.6 99.3 N.A. N.A. 55.7 61.9 53.8 N.A. 41.7 N.A. 46.9 N.A.
P-Site Identity: 100 86.6 100 100 N.A. 100 100 N.A. N.A. 86.6 53.3 86.6 N.A. 93.3 N.A. 93.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 73.3 100 N.A. 100 N.A. 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 91 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 91 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 28 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 100 0 0 0 10 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 100 0 0 0 0 0 91 0 0 0 0 91 0 % R
% Ser: 0 0 0 0 0 91 0 0 0 0 0 55 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 100 0 0 0 46 0 0 0 % T
% Val: 0 0 0 0 0 0 73 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 91 0 0 0 0 0 0 0 0 100 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _