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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNB1
All Species:
4.55
Human Site:
S377
Identified Species:
10
UniProt:
P11230
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11230
NP_000738.2
501
56698
S377
M
P
E
P
P
H
C
S
S
P
G
S
G
W
G
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
R377
V
P
R
G
L
A
R
R
P
A
K
G
K
L
A
Rhesus Macaque
Macaca mulatta
XP_001108848
500
55982
S376
M
P
E
P
P
H
C
S
S
P
G
S
G
W
G
Dog
Lupus familis
XP_546591
504
56778
D380
P
P
P
V
A
L
R
D
S
P
G
S
G
W
G
Cat
Felis silvestris
Mouse
Mus musculus
P09690
501
56912
L377
L
P
E
P
H
H
S
L
S
P
R
S
G
W
G
Rat
Rattus norvegicus
P25109
501
57008
F377
L
P
E
P
H
H
S
F
S
P
R
S
G
W
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520020
344
39644
A250
P
S
R
F
Q
A
E
A
S
G
P
D
L
R
R
Chicken
Gallus gallus
P02713
514
58907
R373
G
P
P
Q
A
T
R
R
R
S
S
L
G
L
M
Frog
Xenopus laevis
P49579
489
56328
P365
T
P
L
P
V
A
P
P
P
R
Q
V
T
S
T
Zebra Danio
Brachydanio rerio
XP_001341867
492
56460
E368
L
E
K
P
A
K
K
E
N
I
Q
A
I
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P04755
521
59883
A372
M
P
G
M
S
M
P
A
H
P
H
P
S
Y
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.3
86.4
91
N.A.
89.8
88.8
N.A.
53.6
41.2
59.2
58.8
N.A.
37.2
N.A.
N.A.
N.A.
Protein Similarity:
100
55
89.6
93.8
N.A.
93.8
93.2
N.A.
58.4
59.9
73.6
73.6
N.A.
58.1
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
53.3
N.A.
66.6
66.6
N.A.
6.6
13.3
13.3
6.6
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
53.3
N.A.
73.3
73.3
N.A.
13.3
13.3
13.3
33.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
28
28
0
19
0
10
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% D
% Glu:
0
10
37
0
0
0
10
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
10
0
0
0
0
0
10
28
10
55
0
55
% G
% His:
0
0
0
0
19
37
0
0
10
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% I
% Lys:
0
0
10
0
0
10
10
0
0
0
10
0
10
0
0
% K
% Leu:
28
0
10
0
10
10
0
10
0
0
0
10
10
19
0
% L
% Met:
28
0
0
10
0
10
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
19
82
19
55
19
0
19
10
19
55
10
10
0
0
0
% P
% Gln:
0
0
0
10
10
0
0
0
0
0
19
0
0
0
0
% Q
% Arg:
0
0
19
0
0
0
28
19
10
10
19
0
0
10
19
% R
% Ser:
0
10
0
0
10
0
19
19
55
10
10
46
10
19
0
% S
% Thr:
10
0
0
0
0
10
0
0
0
0
0
0
10
0
10
% T
% Val:
10
0
0
10
10
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
46
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _