Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHRNB1 All Species: 25.76
Human Site: T84 Identified Species: 56.67
UniProt: P11230 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11230 NP_000738.2 501 56698 T84 V Y L D L E W T D Y R L S W D
Chimpanzee Pan troglodytes Q5IS76 494 56903 N91 L W L R H I W N D Y K L R W D
Rhesus Macaque Macaca mulatta XP_001108848 500 55982 T84 V Y L D L E W T D Y R L S W D
Dog Lupus familis XP_546591 504 56778 T84 V Y L D L E W T D Y R L S W D
Cat Felis silvestris
Mouse Mus musculus P09690 501 56912 T84 V Y L D L E W T D Y R L S W D
Rat Rattus norvegicus P25109 501 57008 T84 V Y L D L E W T D Y R L S W D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520020 344 39644
Chicken Gallus gallus P02713 514 58907 S83 V W I E M Q W S D Y R L R W D
Frog Xenopus laevis P49579 489 56328 N81 V Y L E M A W N D Q R L S W D
Zebra Danio Brachydanio rerio XP_001341867 492 56460 N83 V M M N L E W N D Y R L S W N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P04755 521 59883 Y85 V W L R L V W Y D Y Q L Q W D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 36.3 86.4 91 N.A. 89.8 88.8 N.A. 53.6 41.2 59.2 58.8 N.A. 37.2 N.A. N.A. N.A.
Protein Similarity: 100 55 89.6 93.8 N.A. 93.8 93.2 N.A. 58.4 59.9 73.6 73.6 N.A. 58.1 N.A. N.A. N.A.
P-Site Identity: 100 46.6 100 100 N.A. 100 100 N.A. 0 53.3 66.6 66.6 N.A. 60 N.A. N.A. N.A.
P-Site Similarity: 100 66.6 100 100 N.A. 100 100 N.A. 0 93.3 80 86.6 N.A. 73.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 46 0 0 0 0 91 0 0 0 0 0 82 % D
% Glu: 0 0 0 19 0 55 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 10 0 73 0 64 0 0 0 0 0 0 91 0 0 0 % L
% Met: 0 10 10 0 19 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 28 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 10 10 0 10 0 0 % Q
% Arg: 0 0 0 19 0 0 0 0 0 0 73 0 19 0 0 % R
% Ser: 0 0 0 0 0 0 0 10 0 0 0 0 64 0 0 % S
% Thr: 0 0 0 0 0 0 0 46 0 0 0 0 0 0 0 % T
% Val: 82 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 28 0 0 0 0 91 0 0 0 0 0 0 91 0 % W
% Tyr: 0 55 0 0 0 0 0 10 0 82 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _